Penicillamine: Uses, Interactions, Mechanism of Action
2005年6月13日 · Penicillamine inhibits macrophages, decreases IL-1 and the number of T-lymphocytes, and prevents collagen cross linkage. In Wilson's disease it binds copper, …
Penicillamine - Wikipedia
Penicillamine is a tri functional organic compound, consisting of a thiol, an amine, and a carboxylic acid. It is an amino acid structurally similar to cysteine, but with geminal dimethyl substituents …
Penicillamine Uses, Side Effects & Warnings - Drugs.com
2023年8月4日 · Penicillamine is a chelating (KEE-late-ing) agent that binds to excess copper and removes it from the blood stream. In certain conditions, excess copper can build up in the …
Penicillamine - StatPearls - NCBI Bookshelf
2023年3月27日 · Penicillamine can chelate heavy metals such as copper, lead, and mercury and form a soluble complex that is renally excreted in the urine. It also can combine and form …
Cuprimine, Depen (penicillamine) dosing, indications, interactions ...
For the treatment of Wilson's disease, penicillamine binds to copper and helps it to be removed from the body. Decreasing copper levels helps to improve liver function and the...
D-Penicillamine - SpringerLink
2016年10月17日 · D-penicillamine (DPA) is a heavy metal chelator and is the drug of choice for management of Wilson’s disease, a copper-overload disease state. It may also be effective in …
Penicillamine Monograph for Professionals - Drugs.com
Used to promote excretion of copper in the treatment of Wilson disease (hepatolenticular degeneration). Use in conjunction with a low copper diet. Improves neurologic, corneal, …
Penicillamine: MedlinePlus Drug Information
Penicillamine is in a class of medications called heavy metal antagonists. It works to treat Wilson's disease by binding to the extra copper in the body and causing it to leave the body through the …
Penicillamine Oral: Uses, Side Effects, Interactions, Pictures ... - WebMD
For the treatment of Wilson's disease, penicillamine binds to copper and helps it to be removed from the body. Decreasing copper levels helps to improve liver function and the...
Penicillamine increases free copper and enhances oxidative stress …
Penicillamine (PA) makes 10-50% of the patients with neurologic symptoms neurologically worse at the early stage of administration. The aim of this study was to determine how the copper …