The low power view of the histology of pemphigus foliaceus is of a superficial epidermal blistering process. The low power clues include loss of the stratum corneum, increased prominence of the granular layer, or visible superficial epidermal separation with blister formation (Figure 1).

Aug 8, 2023 · Pemphigus foliaceus involves immunoglobulin G (IgG) antibodies directed against desmoglein-1 (Dsg1) found in the granular layer of the epidermis. This activity describes the evaluation and management of pemphigus foliaceus and highlights the role of the interprofessional team in improving care for affected patients. Objectives:

Pemphigus foliaceus is characterised by blistering lesions on otherwise healthy-looking skin. Blisters tend to form when the skin is rubbed (Nikolsky sign. There are currently six subtypes: Pemphigus erythematosus; Pemphigus herpetiformis; Endemic pemphigus foliaceus; IgA pemphigus foliaceus; Paraneoplastic pemphigus foliaceus; Drug-induced ...

Pemphigus foliaceus (PF) is an acquired autoimmune blistering disease in which the body’s immune system produces immunoglobulin G (IgG) autoantibodies that target the intercellular adhesion glycoprotein desmoglein-1 (dsg-1).

Pemphigus foliaceus is an autoimmune blistering disease of the skin. [1] Pemphigus foliaceus causes a characteristic inflammatory attack at the subcorneal layer of epidermis, which results in skin lesions that are scaly or crusted erosions with an erythematous (red) base. [2] Mucosal involvement is absent even with widespread disease. [3]

pemphigus vulgaris (PV), in which blisters form within the deepest layers of the epidermis. The second pemphigus group includes entities causing blisters confined to the superficial epidermis, of which, pemphigus foliaceus (PF) is the most common. Generally, forms …

Pemphigus foliaceus is a rare, more benign form of pemphigus seen in adults and characterized by widespread patches and fragile blisters, erosions, and scaly crust. From: Modern Surgical Pathology (Second Edition), 2009

Aug 8, 2023 · Pemphigus is a potentially life-threatening, autoimmune blistering disease characterized by the presence of circulating antibodies against desmogleins, key components of the integrity of epidermal intercellular adhesion. However, in contrast to pemphigus vulgaris (PV) where mucosal lesions are class …

Pemphigus foliaceus is an acquired autoimmune blistering disease in which the body's immune system produces IgG autoantibodies that target the intercellular adhesion glycoprotein desmoglein-1, which is principally expressed in the granular layer of the epidermis, resulting in the loss of intercellul …

Clinicopathologic and serologic findings were consistent with pemphigus foliaceus, an autoimmune blistering disorder characterized by autoantibodies against Dsg1. 1, 2 Pemphigus foliaceus presents with superficial flaccid blisters and scaly, crusted erosions that primarily affect seborrheic areas while sparing mucous membranes. 1, 2 Drug ...