Pemphigus foliaceus is a rare relatively benign form of pemphigus. In New Zealand pemphigus foliaceus is more often encountered than its more serious relative pemphigus vulgaris , although worldwide pemphigus vulgaris is more common.

Special stains in pemphigus foliaceus. Direct immunofluorescence is a critical component of the workup, but requires a separate specimen transported in appropriate media. A positive result is the presence of intercellular IgG and C3 predominantly within the superficial layers of the epidermis (Figure 6). Pemphigus foliaceus – direct ...

DermNet pages about pemphigus. Benign familial pemphigus Brazilian pemphigus foliaceus Drug-induced pemphigus Endemic pemphigus foliaceus Familial benign pemphigus pathology IgA pemphigus Paraneoplastic pemphigus Paraneoplastic pemphigus pathology Pemphigus foliaceus Pemphigus foliaceus pathology Pemphigus vulgaris Pemphigus vulgaris images

Thiol drugs cause pemphigus foliaceus. Pemphigus foliaceus presents with erythematous, scaly or crusted plaques. Vesicles, bullae and erosions may or may not be present. It most commonly affects the trunk. The oral mucosa is not involved. Non-thiol drugs most commonly cause pemphigus vulgaris.

Using Nikolsky’s original definition strictly, his eponymous sign is the physical splitting of the epidermis creating an erosion (partial loss of the epidermis) following the application of a shearing force to the surface of the skin seen in pemphigus foliaceus. However, with time the use of the sign has broadened to include other intraepidermal disorders including pemphigus vulgaris …

Pemphigus vulgaris is a chronic vesiculobullous skin disorder characterised by autoantibodies against desmoglein 3, which is a component of the desmosome (an intracellular adhesion molecule). Disruption of keratinocyte adhesion leads to superficial blistering and erosion affecting the skin and/or mucous membranes. Histology of pemphigus vulgaris

Aoki V, Rivitti A, Diaz L, Cooperative Group on Fogo Selvagem Research. Update on fogo selvagem, an endemic form of pemphigus foliaceus. Dermatol 2015; 42: 18–26. PubMed Central; Bastuji-Garin S, Suissi R, Blum L, et al. Comparative epidemiology of pemphigus in Tunisia and France: unusual incidence of pemphigus foliaceus in young Tunisian women.

2021年7月21日 · Pemphigus vulgaris is a rare autoimmune disease that is characterised by painful blisters and erosions on the skin and mucous membranes, most commonly inside the mouth. It accounts for 70% of all pemphigus cases worldwide. Images below show …

Intercellular space staining pattern (chicken-wire), pemphigus vulgaris. Intercellular space staining pattern (chicken-wire), pemphigus foliaceus. Linear IgG deposition on basement membrane zone, bullous pemphigoid. Linear IgA deposition on basement membrane zone, linear IgA bullous dermatosis. Vascular staining pattern in dermal vessels for IgM.

2021年11月15日 · In at least some cases of IEN-type IgA pemphigus, the autoantigens are desmoglein 1, desmoglein 3, and an unspecified transmembrane protein. What is the differential diagnosis for IgA pemphigus? Other conditions that should be considered in the differential diagnosis include: Bacterial skin infection; Dermatitis herpetiformis; Pemphigus foliaceus