12595-1-AP targets PANX1 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples. PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. PANX1, also named as MRS1, belongs to the pannexin family.

Monoclonal Antibody for studying PANX1. Validated for IP, WB. Available in 2 sizes. Highly specific and rigorously validated in-house, Pannexin-1 (D9M1C) Rabbit Monoclonal Antibody (CST #91137) is ready to ship.

2025年3月30日 · PANX1 (Pannexin 1) is a Protein Coding gene. Diseases associated with PANX1 include Oocyte/Zygote/Embryo Maturation Arrest 7 and Female Infertility Due To Oocyte Meiotic Arrest. Among its related pathways are Response of endothelial cells to shear stress and Toll-Like receptor Signaling Pathways.

Fabgennix Anti-Pannexin 1 Polyclonal, Catalog # PANX1-101AP. Tested in Western Blot (WB), Immunoprecipitation (IP) and ELISA (ELISA) applications. This antibody reacts with Human samples. Supplied as 200 µL purified antibody (0.5-1.5 mg/mL).

Panx1 普遍表达并在质膜中形成七聚体通道，介导旁分泌和自分泌信号。 除了参与炎症反应外，Panx1 通道已被证明有助于不同的细胞死亡模式（即细胞焦亡、坏死和细胞凋亡）。

Panx1 is ubiquitously expressed and forms heptameric channels in the plasma membrane mediating paracrine and autocrine signaling. Besides their involvement in the inflammatory response, Panx1 channels have been shown to contribute to different modes of cell death (i.e., pyroptosis, necrosis and apoptosis).

2021年9月21日 · Pannexin 1（Panx 1）是一种与缝隙连接相关的大孔膜通道，对ATP具有很高的通透性，广泛表达于哺乳动物各种组织细胞中 。 2014年，Bravo等 在大鼠坐骨神经损伤疼痛模型上，首次发现脊髓内表达的Panx1对慢性NP的发生、发展起着重要作用，之后在多种动物疼痛模型上又相继发现，感觉神经节及外周免疫细胞中表达的Panx1在NP中也起着关键作用 。 鉴于Panx1通道对慢性NP发生、发展机制的研究意义以及新药研制的现实应用意义，本文对Panx1 …

PANX1 is 48-kDa protein which contains 4 transmembrane domains and cytoplasmic N and C termini. It is a mediator of find-me signal/nucleotide release from apoptotic cells. Western blot for Panx1 was also seen in two bands at 45~50 kDa and ~90 kDa. The band of ~90 kDa corresponding to the Panx1 dimer size. (PMID: 24590064, PMID: 19009624)

这种蛋白质和 pannexin 2 在中枢神经系统 (CNS) 中大量表达，并在各种神经元群中共表达。 对非洲爪蟾卵母细胞的研究表明，这种蛋白质单独和与 pannexin 2 结合可能形成具有不同特性的细胞类型特异性间隙连接。 [RefSeq 提供，2008 年 7 月] The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions.

Pannexin 1 antibody LS-C334871 is an unconjugated rabbit polyclonal antibody to Pannexin 1 (PANX1) from human. It is reactive with human and mouse. Validated for WB. A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PANX1 (NP_056183.2).