Dermatologic Manifestations of Pellagra Clinical Presentation - Medscape
2022年5月13日 · Lesions may extend up the arm in the glove or gauntlet form of pellagra. The epidermis of the fingers thickens, and the articular folds disappear. Painful fissures develop on the palms and...
Pellagra (vitamin B3 or niacin deficiency) - DermNet
Pellagra is a systemic disease caused by vitamin B3 (niacin) deficiency. It is characterised by the 4 D’s — dermatitis, diarrhoea, dementia and, if untreated, death. The name ‘pellagra’ is derived from the Italian ‘pelle agra’ meaning sour or rough skin. Who gets pellagra?
糙皮病 - 维基百科，自由的百科全书
糙皮病 又称癞皮病（英語： pellagra），是一种 維生素缺乏症，主要诱因是缺乏 维生素B3 （烟酸）和 蛋白质，特别是含必需氨基酸 色氨酸 的蛋白质。 [1] 色氨酸能被转化为烟酸，大约60mg色氨酸能被转化成1mg烟酸，过程中需要维生素B 1 、B 2 和B 6 的参与。 [2] 因此色氨酸含量丰富但不含烟酸的食物，比如 牛奶 也能有效预防糙皮病。 然而，如果通过食物摄入的色氨酸全部被用于 蛋白质 合成，则仍有可能引起糙皮病。 糙皮病是一种地区性流行病，主要发生于 非洲 、 墨西 …
Pellagra: Definition, Symptoms & Treatment - Cleveland Clinic
Pellagra is a systemic disease caused by a severe deficiency of niacin (vitamin B3). It affects the whole body and can eventually lead to death. Primary pellagra is caused by a lack of niacin in your diet. It usually occurs in poor and food-limited populations. Secondary pellagra can occur when your body is unable to absorb the niacin you eat.
Pellagra: A Non-Eradicated Old Disease - PMC
Pellagra is a nutritional disorder caused by niacin (vitamin B3) deficiency, which leads to systemic disease with clinical manifestations from the skin, gastrointestinal tract and the nervous system. 1-3 Niacin forms into nicotinic acid and nicotinamide, which serve as precursors of two important coenzymes of cellular metabolism, namely ...
Pellagra (from Italian pella agra, i.e., rough skin) is a disease triggered by abnormal-ities in the metabolism of niacin (known also as: nicotinic acid (and nicotinamide), vitamin B3, and vitamin PP (Pellagra Preventing factor)). The historical cause of the disease was an unbalanced diet, such as consumption of mainly corn products [1, 2].
Diagnosis and Treatment of Pellagra - Medscape Education
2024年11月22日 · Pellagra is the late stage of severe niacin deficiency. Primary pellagra results from inadequate nicotinic acid (ie, niacin) and/or tryptophan intake in the diet. Secondary pellagra occurs when adequate quantities of niacin are present in the diet, but other diseases or conditions interfere with its absorption and/or processing.
Dermatologic Manifestations of Pellagra Differential Diagnoses - Medscape
2022年5月13日 · Lupus erythematosus acutus et subacutus disseminatus - Distinguished by the general state, variable skin manifestation, infiltrates, red wine–colored transient erythemas on the palms...
Pellagra: Dermatitis, dementia, and diarrhea - Hegyi - 2004 ...
2003年12月24日 · Pellagra defines systemic disease as resulting from a marked cellular deficiency of niacin. It is characterized by 4 “D’s”: diarrhea, dermatitis, dementia, and death. Diagnosis of pellagra is difficult in the absence of the skin lesions, and is often facilitated by the presence of characteristic ones.
Pellagra results from a niacin and/or tryptophan deficient diet. Earliest recorded reports of pellagra were made almost 250 years ago. The condition quickly became associated with maize-based diets and was seen to spread throughout Europe following the introduction of maize as a staple crop from its original home in the New World.