PABPC1 Gene - GeneCards | PABP1 Protein | PABP1 Antibody
2025年3月30日 · PABPC1 (Poly(A) Binding Protein Cytoplasmic 1) is a Protein Coding gene. Diseases associated with PABPC1 include Rift Valley Fever and Dengue Virus. Among its …
RNA结合蛋白PABPC1的功能及生物学作用 - pibb.ac.cn
本文将主要介绍PABPC1的结构、表达调控、功能及其生物学作用. 多聚腺苷酸结合蛋白（poly (A)binding protein,PABP)是一类高度保守的RNA结合蛋白，普遍存在于真核生物中，能够特异 …
PABPC1——mRNA stability, protein translation and tumorigenesis
Mammalian poly A-binding proteins (PABPs) are highly conserved multifunctional RNA-binding proteins primarily involved in the regulation of mRNA translation and stability, of which …
PABPC1 - Wikipedia
Polyadenylate-binding protein 1 is a protein that in humans is encoded by the PABPC1 gene. [5] The protein PABP1 binds mRNA and facilitates a variety of functions such as transport into …
Selective translational control by PABPC1 phase separation …
2025年3月18日 · Our high-throughput CRISPR–Cas9 screening identified poly (A) binding protein cytoplasmic 1 (PABPC1) as a driver for CML progression in the BC stage. PABPC1 …
陈玲玲组揭示环形RNA在神经发育过程中转运与功能调控新机制
2024年6月5日 · PABPC1 是一种核质穿梭蛋白，过往的研究显示其在调控 mRNA 的加工转运、稳定性维持和翻译过程中发挥重要功能。 该研究发现， H9 细胞核中的 PABPC1 能够结合这些 …
PABPC1 poly(A) binding protein cytoplasmic 1 [ Homo sapiens …
2025年3月16日 · HIV-1 Rev interacting protein, poly (A) binding protein 1 (PABPC1), is identified by the in-vitro binding experiments involving cytosolic or nuclear extracts from HeLa cells. The …
Altered nucleocytoplasmic export of adenosine-rich circRNAs by PABPC1 …
2024年6月20日 · In the H9 nucleus, newly produced (A)-rich circRNAs are bound by PABPC1 and trapped by the nuclear basket protein TPR to prevent their export. Modulating (A)-rich motifs in …
Nature子刊：马艳妮/余佳/赵萌/王小团队揭示，靶向相分离，治疗 …
pabpc1 蛋白通过形成生物分子凝聚体，优先提高了多个具有长且高度结构化的 5' 非翻译区（5' utr）的白血病致病 mrna 的翻译效率。
poly (A) 结合蛋白胞质 1（PABPC1）基因 | MCE
该蛋白质在细胞核和细胞质之间穿梭，并通过 RNA 识别基序与真核信使 RNA 的 3' poly (A) 尾部结合。 该蛋白与 poly (A) 的结合促进核糖体募集和翻译起始；它也是 poly (A) 缩短所必需的， …
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