PTEN - Pathology Outlines
2025年1月20日 · Immunohistochemical stains show wild type expression of p53, intact expression of mismatch repair proteins (MLH1, PMS2, MSH2, MSH6) and loss of PTEN expression. The …
Comparison of immunohistochemistry and next-generation …
2023年11月1日 · Immunohistochemistry (IHC) is commonly used as an ancillary tool for diagnosing, prognostic stratification, and establishing the treatment plan in routine pathology …
PTEN - NeoGenomics
2025年1月22日 · Immunohistochemistry (IHC) Phosphatase and tensin homolog (PTEN) is a tumor suppressor gene that is mutated in a wide range of cancers. PTEN plays a role in cell …
Clinical and pathological associations of PTEN expression in …
2020年6月18日 · PTEN loss is a putative driver in histotypes of ovarian cancer (high-grade serous (HGSOC), endometrioid (ENOC), clear cell (CCOC), mucinous (MOC), low-grade serous …
PTEN Protein Loss by Immunostaining: Analytic Validation and …
2011年10月14日 · We show that PTEN protein expression evaluated by immunohistochemistry (IHC), using a new commercially available monoclonal antibody, is simple to conduct and …
Immunopathologic Assessment of PTEN Expression
2015年12月11日 · The PTEN protein is ubiquitously expressed in the majority of human tissues, and it is readily measurable by immunohistochemistry (IHC). Thus normal tissues can serve as …
胡夕春/杨文涛教授：CAPItello-291揭示PTEN IHC检测具有疗效相 …
2024年12月27日 · pten ihc检测通过使用特定的抗体与肿瘤细胞内的pten蛋白发生反应，能够直接检测pten蛋白的表达水平，有效评估由基因改变或表观遗传调控等因素导致的pten蛋白功能性 …
PTEN loss detection in prostate cancer: comparison of PTEN ...
2017年7月10日 · PTEN deletion is an established prognostic biomarker in prostate cancer. We compared PTEN immunohistochemistry (IHC) and PTEN fluorescence in situ hybridization …
SIRT7 facilitates endometrial cancer progression by regulating PTEN ...
2025年3月27日 · More importantly, the negative PTEN IHC staining is strongly related to a poor survival rate of patients with advanced EC 18. Collectively, these clues have suggested that …
Integrated proteogenomic characterization of localized prostate …
5 天之前 · A IHC staining and quantification for α2,3 and α2,6-sialylation modifications in tumor regions of three proteomic subgroups in the ... we next constructed the Pten/Trp53 double …