iPPI-DB is a database of modulators of protein-protein interactions. It contains exclusively small molecules and therefore no peptides. The data are retrieved from the literature either peer reviewed scientific articles or world patents.

2020年12月9日 · 在转录调控相关的文献中，我们经常能够看到这样的蛋白质相互作用网络（protein protein interaction network，PPI network）。 具体而言，这些相关的文献中首先通过RNA-seq、表达谱芯片或者蛋白质组分析等，找到了在不同分组样本间一系列的差异表达基因或蛋 …

2021年1月8日 · Freely accessible databases of PPI modulators that provide the community with tractable chemical and pharmacological data, as well as powerful tools to query them, are therefore essential to stimulate new drug discovery projects on PPI targets. Here, we present the new version iPPI-DB, our manually curated database of PPI modulators.

2022年5月25日 · 构建PPI网络一般需要使用string数据库获取蛋白互作信息以及进行互作网络的可视化。 下面探究一下STRING数据库的网页和R语言版的使用： 1. STRING 数据库基本介绍. STRING是一个已知和预测的蛋白质-蛋白质相互作用的数据库。 相互作用包括直接 (物理)和间接 (功能)联系;它们源于计算预测、生物之间的知识转移，以及其他 (主要)数据库聚合的交互作用。 STRING中的相互作用有五个主要来源：基因组预测、高通量实验、（保守的）共表达实验、 …

iPPI-DB contains 1650 non-peptide inhibitors (iPPI) across 13 families of Protein-Protein Interactions. The chemical structures, the physicochemical and the pharmacological profiles of these iPPI are manually extracted from the literature and stored in iPPI-DB.

2015年10月1日 · iPPI-DB is a relational database containing the structure, the physicochemical characteristics, the pharmacological data (biochemical and/or cellular binding data) of compounds modulating known PPI targets as well as the profile of the corresponding targets.

2024年10月16日 · 蛋白质-蛋白质相互作用（Protein-Protein Interaction, PPI）是指两个或多个蛋白质通过物理结合形成复合物，进而调控细胞信号传导、代谢、免疫应答等生命活动的过程。

蛋白质互作网络（Protein-Protein Interaction Networks，PPI）是由蛋白通过彼此之间的相互作用构成，来参与生物信号传递、基因表达调节、能量和物质代谢及细胞周期调控等生命过程的各个环节。

For your target protein provide either a PDB code or a UniProt code. An example of the results for the uniprot O04197 code can be found on this page. Option A) For a known PDB 4-letter code. Option B) For a UniProt code. You can download the entire PPI-HotSpot DB and the associated PPI-HotSpot+PDB BM from this page.

This Acti9 product is a flush or surface mounted 6 ways TPN distribution board. It comes with a double door and the door opening side is reversible. The enclosure material is made of steel. The color of the distribution board is white (RAL 9003). The …