
Clinical and immunologic response of patients with advanced solid ...
2008年5月20日 · Background: The clinical and immunologic efficacy of the optimized peptide TERT 572Y (Vx-001) presented by HLA- A*0201 in patients with advanced malignancies was investigated.
Meeting Abstract: 2005 ASCO Annual Meeting - ASCO Publications
2005年6月1日 · Conclusions: TERT 572Y peptide vaccine is well tolerated and effective in eliciting a specific T cell immunity. This is the first clinical trial demonstrating that cryptic peptides are promising candidates for cancer immunotherapy.
Meeting Abstract: 2007 ASCO Annual Meeting - ASCO Publications
2007年6月20日 · Peptide-specific immune responses were monitored by Elispot assay and/or TERT 572Y pentamer staining. Clinical outcome was compared with that of 22 case-matched historical control patients. Results: Thirteen (59%) out of 22 patients completed the vaccination program. Toxicity consisted primarily of local skin reactions.
Sequential administration of the native TERT572 cryptic peptide ...
The aim of this study was to investigate the best administration of telomerase reverse transcriptase (TERT572), an human leukocyte antigen-A*0201-restricted cryptic epitope of telomerase, and its optimized variant TERT (572Y) to elicit specific T …
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A phase I study of the optimized cryptic peptide TERT (572y) in ...
2021年10月12日 · TERT (572Y) peptide vaccine is well tolerated and effective in eliciting specific TERT (572Y) CD8+ lymphocytes in pretreated cancer patients, demonstrating that cryptic peptides could be used in cancer immunotherapy.
CpG oligodeoxynucleotides activate dendritic cells in vivo and …
2006年3月10日 · Immunization against TERT 572Y peptide in the presence of ODN-CpG rather than IFA led to a strong CD8 response and can delayed mortality in an induced tumor model. Study of the CD8 response obtained after antigenic challenge suggested that a functional memory response is induced upon vaccination with ODN-CpG.
(PDF) A Phase I Study of the Optimized Cryptic Peptide TERT<sub>572Y ...
2006年2月1日 · TERT (572Y) peptide vaccine is well tolerated and effective in eliciting specific TERT (572Y) CD8+ lymphocytes in pretreated cancer patients, demonstrating that cryptic peptides could be used...
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Kyocera 1T02HGAUS0 Model TK-572Y, Yellow Toner Cartridge for …
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