Paroxysmal nocturnal hemoglobinuria (PNH) is a rare blood disorder that happens when part of your immune system attacks and damages your red blood cells and platelets. Left untreated, PNH can cause hemolytic anemia, chronic kidney disease or thrombosis (blood clots).

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired, [1] life-threatening disease of the blood characterized by destruction of red blood cells by the complement system, a part of the body's innate immune system.

Jul 31, 2023 · Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disease that presents clinically with a variety of nonspecific symptoms. It causes complications mainly through intravascular hemolysis, thrombosis, and bone marrow failure.

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired blood disorder characterized by the destruction of red blood cells by the body’s complement system. Paroxysmal nocturnal hemoglobinuria (PNH) is not an inherited condition but rather an acquired disease that develops during a person’s lifetime.

Sep 20, 2023 · What Is Paroxysmal Nocturnal Hemoglobinuria? It’s a rare blood disease that stems from your genes. If you have it, your immune system attacks red blood cells in your body and breaks them down.

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired, life-threatening disease of the blood. The disease is characterized by destruction of red blood cells, blood clots, and impaired bone marrow function. PNH is closely related to aplastic anemia.

Mar 19, 2025 · Paroxysmal nocturnal haemoglobinuria (PNH) is a haemolytic anaemia characterised by evidence of intravascular haemolysis such as haemoglobinuria and elevation of plasma lactate dehydrogenase. Diagnosis can be made by flow cytometry of granulocytes and red blood cells, looking for the lack of the ...