2024年11月25日 · PML (promyelocytic leukaemia) bodies are spherical structures in the nucleus that can measure up to 1 µM in diameter. The principal organizing component of PML...

PML nuclear bodies are nucleated by the PML protein, which polymerizes into spherical shells where it concentrates many unrelated partner proteins. Emerging data has connected PML …

Promyelocytic leukemia protein (PML) (also known as MYL, RNF71, PP8675 or TRIM19 [5]) is the protein product of the PML gene. PML protein is a tumor suppressor protein required for the …

PML （promyelocytic leukemia）核体是以PML蛋白为主要骨架成分、定位于细胞核内、直径约0.1-2m的超级蛋白复合体。 PML核体中定位了众多功能蛋白（如P53、UBC9等），赋予 …

PML is a tumour suppressor protein that typically localizes to and is necessary for the formation of nuclear macromolecular structures called promyelocytic leukaemia nuclear bodies (PML-NBs)....

Promyelocytic leukemia (PML) nuclear bodies, membrane-less organelles in the nucleus, play a crucial role in cellular homeostasis. These dynamic structures result from the assembly of …

PML nuclear bodies are matrix-associated domains that recruit an astonishing variety of seemingly unrelated proteins. Since their discovery in the early 1960s, PML bodies have …

2006年11月3日 · PML nuclear bodies (NBs) are nuclear structures that have been implicated in processes such as transcriptional regulation, genome stability, response to viral infection, …

2020年10月1日 · We review recent breakthroughs in the PML field ranging from a revised assembly mechanism to PML-driven genome organization and carcinogenesis. In addition, we …

2018年5月1日 · Promyelocytic leukemia nuclear bodies are membraneless substructures of the nucleus. SUMOylation is for PML, determining nuclear body formation as well as degradation. …