PLGA, PLG, or poly(lactic-co-glycolic) acid (CAS: 26780-50-7) is a copolymer which is used in a host of Food and Drug Administration (FDA) approved therapeutic devices, owing to its biodegradability and biocompatibility. [1]

Poly(lactic-co-glycolic) acid (PLGA) has attracted considerable interest as a base material for biomedical applications due to its: (i) biocompatibility; (ii) tailored biodegradation rate (depending on the molecular weight and copolymer ratio); ...

PLGA is biocompatible and biodegradable, exhibits a wide range of erosion times, has tunable mechanical properties and most importantly, is a FDA approved polymer.

Poly(lactic-co-glycolic acid) (PLGA) is the most often used synthetic polymer within the field of bone regeneration owing to its biocompatibility and biodegradability. As a consequence, a large number of medical devices comprising PLGA have been ...

2014年2月28日 · This paper critically reviews the scientific challenge of manufacturing PLGA-based materials with suitable properties and shapes for specific biomedical applications, with special emphasis on bone tissue engineering.

2023年1月1日 · Poly (lactic-co-glycolic acid) (PLGA) is a biodegradable polymer with a lot of potential in pharmaceutical nanotechnology and novel drug carrier systems due to its superior properties. PLGA is noted for its biocompatibility and biodegradability when hydrolytically degraded into nontoxic compounds, glycolic acid, and lactic acid via natural ...

2012年7月20日 · This review presents why PLGA has been chosen to design nanoparticles as drug delivery systems in various biomedical applications such as vaccination, cancer, inflammation and other diseases.

Polylactic-co-glycolic acid (PLGA) is one of the extensively researched synthetic biodegradable polymers due to its favorable properties. It is also known as a 'Smart Polymer' due to its stimuli sensitive behavior.

Poly-lactic-co-glycolic acid (PLGA) has been the most successful polymeric biomaterial for use in controlled drug delivery systems. There are several different chemical and physical properties of PLGA that impact the release behavior of drugs from ...

2021年6月29日 · Poly (lactide-co-glycolide) (PLGA) is a biodegradable polymer that is used in most long-acting formulations approved by the FDA. PLGA is used to provide sustained release of drug in various long-acting formulations such as microspheres, in situ gel implants, and solid implants. Long-acting formulations offer many advantages compared to ...