Intended useImmunoassay for the quantitative measurement of protein induced by vitamin K absence or antagonist-II (PIVKA‑II) in human serum and plasma. The assay is used as an aid in the diagnosis of hepatocellular carcinoma (HCC).

pivka-ii已被列为肝癌筛查的重要标志物，中国2019年版 《慢性乙型肝炎防治指南》 将pivka-ii检测写入指南中，推荐用于高危人群筛查、辅助诊断、监测治疗效果、作为预后和复发的预测指标。pivka-ii对肝细胞癌诊断的特异性和灵敏度均优于甲胎蛋白，两者联合检测 ...

2021年4月13日 · PIVKA-II is a promising serum biomarker for the HCC diagnosis that can be used as a supplement for AFP. The combined diagnosis of the two markers greatly improved the diagnostic efficiency of HCC.

2017年9月1日 · Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II) is an efficient biomarker specific for hepatocellular carcinoma (HCC). Some researchers have proved that levels of PIVKA-II reflect HCC oncogenesis and progression. However, the effectiveness of PIVKA-II based on real-world clnical data has barely been studied.

Des-gamma carboxyprothrombin (DCP), also known as protein induced by vitamin K absence/antagonist-II (PIVKA-II), is an abnormal form of the coagulation protein, prothrombin.

Immunoassay for the quantitative measurement of protein induced by vitamin K absence or antagonist-II (PIVKA‐II) in human serum and plasma. The assay is used as an aid in the diagnosis of hepatocellular carcinoma (HCC). The results must be interpreted in conjunction with other methods in accordance with standard clinical management guidelines.

PIVKA-II (Protein Induced by Vitamin K Absence or Antagonist-II) is a protein-based biomarker used to detect liver cancer in its early stages. This test is more effective than AFP alone in diagnosing hepatocellular carcinoma.

2025年2月4日 · In this study, we aimed to determine the PIVKA-II response and investigate the correlation between PIVKA-II and radiologic responses in patients with non-AFP-secreting HCC receiving systemic therapy.

2024年12月16日 · HealthDay News — Among patients with hepatitis C virus (HCV)-related cirrhosis with sustained virological response (SVR) to direct-acting antivirals (DAAs), a serum protein induced by vitamin K...

2023年2月24日 · We have established for the first time the distribution of PIVKA-II in the Singapore population. The distribution of PIVKA-II values in our non-HCC patients was more similar to the healthy individuals in the EU than in Japan.