Human parainfluenza viruses (HPIVs) are the viruses that cause human parainfluenza. HPIVs are a paraphyletic group of four distinct single-stranded RNA viruses belonging to the Paramyxoviridae family. These viruses are closely associated …

2017年11月30日 · 副流感病毒（PIV）是一类具有多形性、有包膜的单股负链 RNA 病毒，属副黏病毒，分为 4 种亚型，PIV-1 和 PIV-3 属于呼吸道病毒属，而 PIV-2 和 PIV-4 属于腮腺炎病毒属。 病毒直径 125-250 nm，包膜由脂质和糖蛋白组成。 糖蛋白有两种：一种为血球凝集素-神经氨酶蛋白（NH），具有红细胞凝集活性和神经氨酶活性；另一种为融合蛋白（F 蛋白），具有促进细胞融合的作用和溶血特性。 发病机制. PIV 所致疾病的发病机制是由病毒复制和宿主免疫应答所介 …

Human parainfluenza virus (PIV) type 3 infections are the second most common cause of serious respiratory tract disease in infants and children (after RSV). Each year, approximately 25% of children <5 years of age experience a clinically significant PIV infection and 2% of them require hospitalization. This virus subtype commonly causes ...

Parainfluenza virus (PIV) is a leading cause of lower respiratory tract infections. Although there are several distinct PIV serotypes, few studies have compared the clinical characteristics and severity of infection among the individual PIV serotypes and between PIV and other pathogens in patients with community-acquired pneumonia.

2024年1月10日 · 1、piv-1和piv-2主要在上呼吸道上皮细胞中复制，所以最常引起上呼吸道感染和婴幼儿哮吼（喉气管炎）。 2、PIV-3主要在下呼吸道复制，所以可致毛细支气管炎和肺炎（重点影响<1岁的儿童）。

2024年7月22日 · 副流感病毒（parainfluenza viruses，PIV）隶属副黏病毒科，为单链RNA病毒，电镜下多呈球型，直径125～250 nm，约有15500个核苷酸，编码6种结构蛋白。 PIV主要侵犯呼吸道黏膜的表层组织，在纤毛上皮细胞内复制和繁殖。

2023年8月21日 · In addition, serotype PIV-3 encodes C, D, and V proteins, PIV-1 encodes a C protein, and PIV-2 encodes a V protein. The HN and F proteins project through the lipid envelope and form the major antigenic targets for neutralizing antibody .

人类副流感病毒 (HPIVs)常常引起儿童下呼吸道感染的一种病毒，其致病性仅次于呼吸道合胞病毒 (RSV)。 与RSV一样，人类副流感病毒可以造成反复发作的上呼吸道感染（如感冒和喉咙痛）。 它也能造成严重的反复感染的下呼吸道疾病（如肺炎，支气管炎和细支气管炎），特别是在老年人中和有免疫缺陷人群中。

2019年1月7日 · Differences in seasonality, clinical presentation, and prevalence between the different PIV serotypes (PIV-1, PIV-2, and PIV-3) were identified. The most common signs/symptoms were cough (88%), productive sputum (55%), fever (63%), and dyspnea (49%).

Parainfluenza refers to a group of viruses — human parainfluenza viruses (HPIVs) — that cause common respiratory infections. This includes illnesses like colds, croup, bronchiolitis, bronchitis and pneumonia. They’re more likely to cause severe illness in children younger than 5, adults older than 65, and people with weakened immune systems.