2021年3月22日 · One type of gene mutation that’s known to affect people with breast cancer is called PIK3CA. A mutation in the PIK3CA gene can cause cells to divide and replicate …

The PIK3CA gene provides instructions for making the p110 alpha (p110α) protein, which is one piece (subunit) of an enzyme called phosphatidylinositol 3-kinase (PI3K). Learn about this …

2013年8月15日 · PIK3CA-related overgrowth spectrum (PROS) encompasses a range of clinical findings in which the core features are congenital or early-childhood onset of segmental/focal …

The phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (the HUGO -approved official symbol = PIK3CA; HGNC ID, HGNC:8975), also called p110α protein, is a class I PI 3 …

2025年3月30日 · PIK3CA (Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha) is a Protein Coding gene. Diseases associated with PIK3CA include Megalencephaly …

Perhaps one of the most interesting and surprising recent findings in the PIK3CA field was the recent report of common hotspot mutations of PIK3CA in two benign skin lesions – epidermal …

2025年3月13日 · Mutations in the PIK3CA gene significantly alter breast cancer’s molecular landscape, influencing tumor growth, survival, and therapeutic resistance. This gene encodes …

PIK3CA encodes the p110α catalytic subunit of phosphatidylinositol 3-kinase (PI3K) which through its role in the PI3K/Akt pathway is important for the regulation of important cellular …

Oncogenic PIK3CA recruits myeloid-derived suppressor cells to shape the immunosuppressive tumour microenvironment in luminal breast cancer through the 5-lipoxygenase-dependent …

PIK3CA is a gene that encodes one piece (a subunit) of an enzyme called phosphatidylinositol 3-kinase. PIK3CA plays a role in the way cell growth, cell survival, and cell migration are controlled.