Prostaglandin E2 (PGE2), also known as dinoprostone, is a naturally occurring prostaglandin with oxytocic properties that is used as a medication. [2][3][4] Dinoprostone is used in labor …

2023年6月5日 · Prostaglandin E2 (PGE2), also known by the name dinoprostone, is a naturally occurring compound involved in promoting labor, though it is also present in the inflammatory …

2020年3月15日 · Prostaglandin E2 (PGE2) is a principal mediator of inflammation in diseases such as rheumatoid arthritis and osteoarthritis. Nonsteroidal anti-inflammatory medications …

Prostaglandin E2 (PGE2), which involves diverse physiological processes via E-type prostanoid (EP) receptor family, favors the regeneration of various organ systems following injury for its …

Prostaglandin E 2 (PGE 2), an essential homeostatic factor, is also a key mediator of immunopathology in chronic infections and cancer. The impact of PGE 2 reflects the balance …

Prostaglandin E 2 (PGE 2) is a bioactive lipid that elicits a wide range of biological effects associated with inflammation and cancer. PGE 2 exerts diverse effects on cell proliferation, …

Prostaglandin E2 (PGE2) is one of the most typical lipid mediators produced from arachidonic acid (AA) by cyclooxygenase (COX) as the rate-limiting enzyme, and acts on four kinds of …

Prostaglandin E2 (PGE2), a principal mediator of inflammation, plays a critical role in cervical ripening. Its biosynthesis in the cervix involves conversion of arachidonic acid to prostaglandin …

2016年3月18日 · We observed that prostaglandin E 2 (PGE 2), through its receptor EP4, is down-regulated in human systemic inflammatory disease. Mice with reduced PGE 2 synthesis …

2024年2月16日 · This study hypothesizes that urinary prostaglandin E2 (PGE2) and PGE2 metabolite (PGEM) excretions are markers of cardiovascular and kidney health, because they …

2023年12月14日 · PGE2, a powerful bioactive lipid, has been proposed as a promising molecule first to increase human HSPC engraftment ability, then as lentiviral TE.

In this review, we describe the current knowledge on the pro-tumoral activity of PGE2 focusing on its role in cancer progression and in the regulation of the tumor microenvironment. The …

2019年1月14日 · Here we found prostaglandin E2 (PGE2) secreted by osteoblastic cells activates PGE2 receptor 4 (EP4) in sensory nerves to regulate bone formation by inhibiting sympathetic …

Prostaglandin E2 (PGE2) participates in blood pressure (BP) regulation through diverse mechanisms involving different tissues and different receptor subtypes. In general, PGE2 …

Epithelial-mesenchymal transition (EMT) is a process in which epithelial cells become mesenchymal stem cells. It is an example of cell plasticity, in which one cell could be changed …

2022年8月1日 · The MSCs in spheroids are activated spontaneously due to low cellular stress (mediated by hypoxia) in these 3D structures [37] and produce important anti-inflammatory …

Prostaglandin E2 (PGE2) is one of the most important biologically active prostanoids found throughout the gastrointestinal tract. Despite the fact that PGE2 regulates many physiological …

2022年11月9日 · Ahmed S, Kim Y. PGE2 mediates hemocyte-spreading behavior by activating aquaporin via cAMP and rearranging actin cytoskeleton via Ca2+. Dev Comp Immunol (2021) …

Prostaglandin E2 (PGE2), a derivative of arachidonic acid, has been identified as a tumorigenic factor in many cancers in recent studies. Prostaglandin E synthase 2 (PTGES2) is an enzyme …

2022年11月10日 · However, the addition of PGE 2 to the inhibitor treatment rescued the gut immunity. DSP1 release was not observed at infection with non-pathogenic pathogens but …