Polypoidal choroidal vasculopathy (PCV) is a disease of the choroidal vasculature. It is present in both men and woman of many ethnicities, characterized by serosanguineous detachments of the pigmented epithelium and exudative changes that can commonly lead to subretinal fibrosis.

2012年12月1日 · Diagnosis: Choose ICG. Regardless of genetics, PCV has a distinctive appearance, particularly on indocyanine green (ICG) angiography, which is currently the best technique for differentiating it from other forms of neovascularization.

2014年5月4日 · On fundus examination, the most suggestive findings of PCV are orange-red subretinal nodules, spontaneous SRH, and either serous or hemorrhagic PED. The presence of one or more of these features suggest a diagnosis of PCV, and ICG should be performed.

This report presents the APOIS PCV Workgroup updated nomenclature of PCV based on our current understanding of PCV using new clinical, imaging, and histopathologic data. We recommend a set of diagnostic criteria for PCV without the need for ICGA that can achieve high sensitivity, specificity, and an AUC when compared with ICGA as the gold standard.

The most important test used to diagnose PCV is a careful dilated eye examination by your retina specialist. In addition, fluorescein and indocyanine green (ICG) angiography may be useful (Figure 2). These 2 tests are able to create detailed images of the retinal and choroidal blood vessels, which can assist your retina specialist in ...

2025年3月12日 · However, non-ICG multimodal PCV analysis using more standard imaging techniques has become more commonly used due to variable availability of ICG angiography at clinical sites and studies have validated and support the accuracy of this approach. 9, 10, 39, 40 This study also only considered combination with ranibizumab anti-VEGF-A therapy, and ...

2018年10月18日 · 吲哚青绿造影检查（ICGA） 是目前诊断PCV的金标准，以下情况需做ICGA检查以确诊是否为PCV ：临床上观察到视网膜下橘黄色的结节、视网膜下自发性的大量出血、浆液性或出血性色素上皮脱离、凹槽状色素上皮脱离、复发的以及慢性的不典型临床病程、具备渗出性AMD的特征但缺乏软性的玻璃膜疣、在荧光血管造影检查中发现多处隐匿的高荧光渗漏、年轻的患者出现AMD的特征。 PCV患者的ICG可以见到：（1）息肉状脉络膜血管病灶，可有单个病变 …

2020年11月17日 · pcv的icga诊断标准如下：存在视网膜下局灶性icga过度荧光 (在注射icg后的前6分钟内)，外加以下至少一项： 分支血管网（branching vascular network, BVN）； 搏动性息肉样病变(pulsatile polypoidal lesion)；

2014年7月18日 · Polypoidal choroidal vasculopathy (PCV) primarily affects pigmented individuals, especially Asians and African-Americans. Typically presents in 7th to 8th decade of life, though may present earlier th

Definite PCV: protruded orange-red elevated lesions on fundus examination and/or characteristic polypoidal lesions on ICGA; Probable PCV: only an abnormal vascular network or occurrence of recurrent hemorrhagic and/or serous detachment of RPE were observed; EVEREST study