
Pathology Outlines - PAX8
2020年10月26日 · Differentiate primary pulmonary carcinomas (PAX8-) from PAX8+ metastatic carcinomas (renal, Müllerian, thyroid) (Appl Immunohistochem Mol Morphol 2019 Feb;27:140) Differentiate renal collecting duct carcinoma (PAX8+ / p63-) from urothelial carcinoma of the upper urinary tract (PAX8- / p63+) (Am J Surg Pathol 2010;34:965)
Pathology Outlines - Stains & CD markers
P glycoprotein p16 p21 p40 p53 p57 p62 (pending) p63 p120 catenin P504S Pan-TRK PAP PAS PAX2 PAX5 PAX8 PCNA PD-1 PDL1 22C3 PDL1 SP142 PDL1 SP263 (pending) PECAM1 perforin (pending) PGP9.5 (pending) PHLDA1 (pending) phosphohistone H3 Pit1 PLAG1 PLAP PMS2 podoplanin PRAME prealbumin (pending) progesterone receptor (PR) …
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2020年7月23日 · High grade serous carcinoma of the ovary is a type of cancer characterized by aggressive behavior and poor prognosis.
Pathology Outlines - Clear cell
2024年5月2日 · PAX8 is positive in both Mesothelioma: Positive for calretinin, mesothelin and CK5/6. Hemangioblastoma: Lack nuclear atypia, prominent nucleoli and necrosis PAX8 negative and inhibin positive (opposite to clear cell RCC) PAX8 negative at extrarenal sites but can be positive in kidney (Appl Immunohistochem Mol Morphol 2019;27:477)
Pathology Outlines - Clear cell carcinoma
2021年7月9日 · PAX8; HNF1β: sensitive but not specific (Mod Pathol 2006;19:83, Pathology 2015;47:105) Napsin A: specific with intermediate sensitivity (Mod Pathol 2015;28:111, Pathology 2015;47:105) AMACR: specific but not sensitive (Pathology 2015;47:105, Appl Immunohistochem Mol Morphol 2020;28:593)
Mesonephric-like adenocarcinoma (uterus / ovary)
2023年6月1日 · The finding of a hormone receptor negative, PAX8, GATA3 and TTF1 positive tumor is highly supportive of the diagnosis of mesonephric-like adenocarcinoma. While mesonephric remnants and mesonephric derived tumors are often found in paracervical or adnexal locations, this is not true of the mesonephric-like tumors in …
Pathology Outlines - Vimentin
2021年1月11日 · Comment: Immunohistochemistry positive for vimentin, PAX8 and ER and negative for TTF1, consistent with endometrial primary. Additional references Moch: WHO Classification of Tumours of the Urinary System and Male Genital Organs, 4th Edition, 2016 , WHO / ISUP grade 4 ( Pathologe 2016;37:355 )
Pathology Outlines - Endometrioid carcinoma
PAX8+, CK7-, CK20+, ER / PR+, wild type p53, patchy / focal p16 Board review style answer #2 D. PAX8+, CK7+, CK20-, ER / PR+, wild type p53, patchy / focal p16
Pathology Outlines - TFE3 rearranged renal cell carcinoma
2024年12月17日 · Answer E is incorrect because TFE3 rRCC is often positive for PAX8 immunohistochemistry. Answer A is incorrect because ccRCC and TFE3 rRCC have similar cancer specific survival (Am J Surg Pathol 2012;36:663). Answer B is incorrect because TFE3 immunohistochemistry is highly sensitive (positive in 95% of cases), though it …
Pathology Outlines - Oncocytoma
2020年9月21日 · Negative keratins and negative PAX8; Positive for melanocytic markers HMB45 and MelanA / MART1; positive for cathepsin K. MiTF associated renal cell carcinoma (TFEB t6;11 can present with oncocytoma-like features) (Cancers (Basel) 2019;11:1110): Morphology can be variable; includes a described biphasic morphology Positive for TFE3 or TFEB and ...