1 天前 · SQSTM1/p62 Antibody detects endogenous levels of total SQSTM1/p62 protein. Human, Mouse, Rat, Monkey. Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly410 of human SQSTM1/p62 protein. Antibodies are purified by protein A and peptide affinity chromatography.

SQSTM1/p62是与泛素结合的适配器蛋白，可能参与调节TNF-alpha、神经生长因子(NGF)和白细胞介素-1对NFKB1的 激活。 可能参与肌细胞肌动蛋白/TTN下游信号转导。

2 天之前 · Sequestosome 1 (SQSTM1, p62) is a ubiquitin binding protein involved in cell signaling, oxidative stress, and autophagy (1-4). It was first identified as a protein that binds to the SH2 domain of p56Lck (5) and independently found to interact with PKCζ (6,7).

Nuclear pore glycoprotein p62 is a protein complex associated with the nuclear envelope. The p62 protein remains associated with the nuclear pore complex -lamina fraction. p62 is synthesized as a soluble cytoplasmic precursor of 61 kDa [ 5 ] followed by modification that involve addition of N-acetylglucosamine residues, [ 6 ] followed by ...

Sequestosome 1 (SQSTM1, p62) is a ubiquitin binding protein involved in cell signaling, oxidative stress, and autophagy (1-4). It was first identified as a protein that binds to the SH2 domain of p56Lck (5) and independently found to interact with PKCζ (6,7).

SQSTM1/p62 Antibody (YA062) is a non-conjugated and Rabbit origined monoclonal antibody about 48 kDa, targeting to SQSTM1/p62. It can be used for WB,IHC-F,IHC-P,ICC/IF,IP assays with tag free, in the background of Human, Mouse.