6 天之前 · Polyclonal Antibody for studying SQSTM1. Validated for WB. Available in 2 sizes. Highly specific and rigorously validated in-house, SQSTM1/p62 Antibody (CST #5114) is …

Sequestosome-1 is a protein that in humans is encoded by the SQSTM1 gene. [5][6][7] Also known as the ubiquitin-binding protein p62, [8] it is an autophagosome cargo protein that …

2019年8月21日 · Using an unbiased yeast two-hybrid screening and complementary approaches, we found that DAXX physically interacts with p62. Cytoplasmic DAXX promotes p62 puncta …

2020年1月23日 · p62/SQSTM1 is an autophagy receptor and signaling adaptor with an N-terminal PB1 domain that forms the scaffold of phase-separated p62 bodies in the cell. The molecular …

Nuclear pore glycoprotein p62 is a protein complex associated with the nuclear envelope. The p62 protein remains associated with the nuclear pore complex -lamina fraction. p62 is synthesized …

2024年3月26日 · We initially observed that endotoxin lipopolysaccharide (LPS) significantly enhanced p62 droplet size in primary resident MPI macrophages (Figure S1A). Similarly, …

2021年12月3日 · Using a variety of cellular models, we show that the p62 N-terminal caspase-6 cleavage product (p62-N) plays a dominant-negative role to block p62-droplet formation. In …

p62 is a highly conserved, multi-domain, and multi-functional adaptor protein critically involved in several important cellular processes. Via its pronounced domain architecture, p62 binds to …

2023年10月5日 · In cells, p62 promotes the assembly and removal of ubiquitinated proteins by forming insoluble cytoplasmic inclusions known as p62 bodies. 21 p62 bodies have liquid-like …