6 天之前 · Sequestosome 1 (SQSTM1, p62) is a ubiquitin binding protein involved in cell signaling, oxidative stress, and autophagy (1-4). It was first identified as a protein that binds to …

Sequestosome-1 is a protein that in humans is encoded by the SQSTM1 gene. [5][6][7] Also known as the ubiquitin-binding protein p62, [8] it is an autophagosome cargo protein that …

2025年3月28日 · SQSTM1/p62 (D5L7G) Mouse mAb recognizes endogenous levels of total SQSTM1/p62 protein. Human, Monkey. Monoclonal antibody is produced by immunizing …

本文综述了p62蛋白的结构特征、分子功能，并系统介绍其在蛋白质稳态和信号通路调控中的多种功能，总结了p62在疾病发生发展中的复杂性与多面性，以期为p62蛋白的功能与相关疾病研 …

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a …

Phospho-SQSTM1/p62 (Thr269/Ser272) Antibody recognizes endogenous levels of SQSTM1 protein only when phosphorylated at Thr269 and Ser272. This antibody may react with either …

2020年12月17日 · p62/SQSTM1 is a multiprotein interaction hub forming cellular punctate structures known as p62 bodies. p62 is centrally involved in the degradation of ubiquitinated …

Results showed that higher MW p62 form, that appeared within minutes of starvation, was rapidly reversed by bovine serum albumin (BSA) (Figure 7A, line 6) or human serum albumin (results …

Immunofluorescence analysis of SQSTM1/p62 in Hela using p62/SQSTM1 antibody. Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy …

由基因SQSTM1编码的p62 / SQSTM1被广泛称为选择性自噬的衔接蛋白，以促进易于聚集的蛋白质降解。它也是一种应力诱导的支架蛋白，参与Nrf2活化以抵抗氧化应激。