The p38 Pathway: From Biology to Cancer Therapy - PMC
Mitogen-activated protein kinase (MAPK) cascades are signaling components that show a high degree of conservation throughout evolution and play a key role in converting extracellular …
MAPK signal pathways in the regulation of cell proliferation in ...
2002年3月1日 · At least three MAPK families have been characterized: extracellular signal-regulated kinase (ERK), Jun kinase (JNK/SAPK) and p38 MAPK.
p38 MAPK Pathway | Cell Signaling Technology
2025年3月28日 · Interactive p38 MAPK pathway. Learn how p38 MAPK is involved in regulation of HSP27, MAPKAPK-2, MAPKAPK-3, & several transcription factors.
p38 MAP kinases: key signalling molecules as therapeutic ... - Nature
2003年9月1日 · Ma, X. L. et al. Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and …
Activation and signaling of the p38 MAP kinase pathway
2005年1月1日 · An inhibitor of p38 mitogen-activated protein kinase prevents insulin-stimulated glucose transport but not glucose transporter translocation in 3T3-L1 adipocytes and L6 …
p38 MAPK : stress responses from molecular mechanisms to therapeutics …
The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK. Mol. Cell. …
p38 MAP-Kinases pathway regulation, function and role
2007年8月1日 · p38 MAPK controls progression of myoblasts differentiation at multiple levels: transcription factor activity, chromatin remodelling and turnover of mRNAs encoding certain …
p38(MAPK): stress responses from molecular mechanisms to ... - PubMed
The p38(MAPK) protein kinases affect a variety of intracellular responses, with well-recognized roles in inflammation, cell-cycle regulation, cell death, development, differentiation, …
The p38 Pathway: From Biology to Cancer Therapy - PubMed
2020年3月11日 · The p38 MAPK pathway is well known for its role in transducing stress signals from the environment. Many key players and regulatory mechanisms of this signaling cascade …
Mechanisms and functions of p38 MAPK signalling - PubMed
2010年8月1日 · The p38 MAPK (mitogen-activated protein kinase) signalling pathway allows cells to interpret a wide range of external signals and respond appropriately by generating a …
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