Osteocytes are simply osteoblasts trapped in the matrix that they secrete. They are networked to each other via long cytoplasmic extensions that occupy tiny canals called canaliculi, which are used for exchange of nutrients and waste through gap junctions.

osteocyte, a cell that lies within the substance of fully formed bone. It occupies a small chamber called a lacuna, which is contained in the calcified matrix of bone. Osteocytes derive from osteoblasts, or bone-forming cells, and are essentially osteoblasts surrounded by …

Of the major cell types in bone, osteoblasts and osteoclasts have been defined by their respective functions of bone formation and bone resorption, but osteocytes were defined primarily by their morphology and location embedded within mineralized bone matrix rather than by their function.

2020年6月8日 · Osteocytes, the most abundant and long-lived cells in bone, are the master regulators of bone remodeling. In addition to their functions in endocrine regulation and calcium and phosphate...

2020年1月1日 · Osteocytes represent 90–95% of all bone cells in the adult skeleton. In human bone, they have a long life (up to 25 years), while the mean half life of osteoblasts is 150 days (Bonewald, 2011). The osteocyte is a descendant of osteoblasts. They come from mesenchymal stem cells in the bone marrow.

Osteocytes are cells embedded in bone, able to modify their surrounding extracellular matrix via specialized molecular remodeling mechanisms that are independent of the bone forming osteoblasts and bone-resorbing osteoclasts.

Osteocytes are stellate-shaped cells within the mineralized bone matrix that comprise 90—95% of all bone cells, therefore, they are the most abundant bone cell in the adult skeleton. The morphology of the osteoblast, a plump polygonal cell, changes dramatically as it becomes an osteocyte with reduced cytoplasm and numerous dendritic processes.

Our current knowledge of osteocytes lags behind what we know of the properties and functions of both osteoblasts and osteoclasts. However, the striking structural design of bone predicts an important role for osteocytes, and novel techniques have allowed this gap in knowledge to shrink rapidly in the past years.

2020年6月8日 · Osteocytes, the most abundant and long-lived cells in bone, are the master regulators of bone remodeling. In addition to their functions in endocrine regulation and calcium and phosphate metabolism, osteocytes are the major responsive cells in force adaptation due to mechanical stimulation.

2020年2月10日 · Osteocytes are cells embedded in bone, able to modify their surrounding extracellular matrix via specialized molecular remodeling mechanisms that are independent of the bone forming osteoblasts and bone-resorbing osteoclasts.