2023年7月31日 · Osteochondral allografts provide viable hyaline cartilage with metabolically active chondrocytes and subchondral bone with remodeling potential to the articular surface and promising results according to evidence.

Osteochondral allograft transplantation involves taking a larger amount of tissue from a cadaver rather than from the patient’s own knee.

Osteochondral allograft transplantation (OCA) treats symptomatic focal cartilage defects with satisfactory clinical results. To comprehensively analyze the characteristics and clinical outcomes of OCA for treating articular cartilage defects. ...

Osteochondral allograft (OCA) transplantation offers a single-stage solution to address large chondral and osteochondral defects by resurfacing focal cartilage defects with mature hyaline cartilage. To date, OCA transplantation of the knee has demonstrated excellent clinical outcomes and long-term survivorship.

While several treatment options exist, osteochondral allograft (OCA) transplantation for the knee has been used successfully in primary management of large chondral or osteochondral defects and salvage of previously failed cartilage repair.

2023年6月10日 · These evidence-based pearls for osteochondral allograft handling optimize metabolic activity, reduce thermal necrosis, reduce antigenicity with removal of marrow elements, enhance biologic potential, and maintain chondrocyte viability to optimize biologic healing and clinical success.

Fresh osteochondral allograft (OCA) transplantation has been shown to be a reliable surgical procedure to manage a wide array of high-grade focal chondral lesions, with or without subchondral bone involvement.

2025年1月18日 · Although various surgical options exist to restore the articular cartilage, osteochondral allograft (OCA) transplantation is the authors’ preferred method of treatment for medium- to large-sized articular cartilage defects (>20 mm diameter) in the femur and patella.

4 天之前 · Osteochondral allograft (OCA) transplantation is an effective single-staged procedure used to resurface large defects > 2 cm 2 with mature hyaline articular cartilage, while simultaneously addressing underlying subchondral bone deficits. In isolation, ...

2021年12月10日 · Osteochondral allograft transplantation (OCA) is a tissue-based cartilage reconstruction or replacement method which can be also performed for chondral and osteochondral lesions of larger size.