An integrated transcriptomic cell atlas of human neural organoids
2024年11月20日 · A human neural organoid cell atlas integrating 36 single-cell transcriptomic datasets shows cell types and states and estimates transcriptomic similarity between primary …
Organoids - Nature Reviews Methods Primers
2022年12月1日 · Organoids are derived from either pluripotent or tissue-resident stem (embryonic or adult) or progenitor or differentiated cells from healthy or diseased tissues, such as …
Lineage recording in human cerebral organoids | Nature Methods
2021年12月30日 · Induced pluripotent stem cell (iPSC)-derived organoids provide models to study human organ development. Single-cell transcriptomics enable highly resolved …
Landscape of human organoids: Ideal model in clinics and research
Organoids benefit to drug discovery, disease study, prevention, control, and therapy. Synthetic biology, artificial intelligence and automation integration broaden the role of organoids. In the …
Professor HE, Mu 何睦 - Academic Staff - People - School of …
In the He lab, we are leveraging the power of stem cell biology, live imaging, organoids, and single-cell technologies to understand how the respiratory system develops, repairs, and …
A 3D Bioprinted Cortical Organoid Platform for Modeling Human …
2024年5月30日 · Using organoid growth, viability, cytoarchitecture, proliferation, and transcriptomic benchmarks, this work finds that organoids cultured within the bioprinted …
Liver organoids: updates on generation strategies and biomedical ...
2024年8月7日 · Kim et al. showed that hPSC-derived HE organoid can be efficiently produced without EGF, Noggin, R-spondin 1 and proliferated in the absence of R-spondin 1 and EGF. In …
The role of organoids in cancer research | Experimental …
2023年8月3日 · In the early stage of organoid culture, haematoxylin-eosin (HE) staining and immunohistochemistry are recommended to preliminarily determine the similarity between the …
Organoids — Preclinical Models of Human Disease
2019年2月6日 · An organoid is a three-dimensional construct composed of multiple cell types that originates from stem cells by means of self-organization and is capable of simulating the …
Landscape of human organoids: Ideal model in clinics and research
2024年5月6日 · Organoids benefit to drug discovery, disease study, prevention, control, and therapy. Synthetic biology, artificial intelligence and automation integration broaden the role of …