Organophosphate poisoning is poisoning due to organophosphates (OPs). [4] Organophosphates are used as insecticides, medications, and nerve agents. [4] Symptoms include increased saliva and tear production, diarrhea, vomiting, small pupils, sweating, muscle tremors, and confusion. [2]

2023年11月12日 · Identify the clinical signs and symptoms indicative of organophosphate toxicity, including manifestations of cholinergic toxidromes, such as miosis, diaphoresis, and bronchorrhea.

2024年7月18日 · Organophosphate poisoning occurs when your body reacts to chemical compounds found in certain agricultural products and chemical warfare nerve agents. These compounds affect how your nervous system functions and can lead to life-threatening symptoms.

Organophosphates and carbamates are common causes of poisoning and poison-related deaths worldwide. Organophosphates and carbamates are absorbed through the gastrointestinal tract, lungs, and skin. They inhibit plasma and red blood cell (RBC) cholinesterase, preventing breakdown of acetylcholine, which then accumulates in synapses.

2018年8月29日 · Organophosphate poisoning is a serious medical condition, no matter how small the dose. Long, high-intensity exposures are the most concerning. See a doctor right away if you believe...

The typical toxidrome in organophosphate (OP) poisoning comprises of the Salivation, Lacrimation, Urination, Defecation, Gastric cramps, Emesis (SLUDGE) symptoms. However, several other manifestations are described. We review the spectrum of ...

Decontamination of patients should always be considered to prevent poisoning of medical personnel. Organophosphate (OP) compounds are a diverse group of chemicals used in both domestic and...

2024年3月14日 · Organophosphate poisoning occurs after dermal, respiratory, or oral exposure to either organophosphate pesticides (e.g., chlorpyrifos, dimethoate, malathion, parathion) or nerve agents (e.g., tabun, sarin), causing inhibition of acetylcholinesterase at nerve synapses.

2024年12月18日 · Organophosphate Poisoning: common cause of poisoning in the developing world; covalent bonding with inactivation of acetylcholinesterase; results in cholinergic crisis

Orgnophosphate poisoning (OPP) is a major global health problem, with 1 million serious accidental and 2 million suicidal poisonings due to insecticides worldwide, every year, of which 200,000 die; most of these deaths occur in developing countries including India and Sri Lanka. OPP is the most common mode of suicidal poisoning in India.