2-naphthalamine X 2-NH2,4-X NO2 CN Cl Br I COOCH3 OCH3 NH2,6-X NO2 Cl OCH3 OH NH2,7-X NO2 Cl OCH3

2017年10月27日 · In short, the stronger the acid, the smaller the pKa value and strong acids have weak conjugate bases. pKa values describe the point where the acid is 50% dissociated (i.e. deprotonated). Below are tables that include determined pKa values for various acids as determined in water, DMSO and in the gas Phase.

2021年3月18日 · The pKa of the conjugate acid of -OCH3 is 15, and the pKa of the conjugate acid of -F is 3.1. -OCH3 is the stronger base, so I would think it is the better leaving group.

Electronic Supplementary Material (ESI) for Organic & Biomolecular Chemistry. This journal is © The Royal Society of Chemistry 2014 Table S1. Chemical structures and pKa of some …

pKa Table: Effect of electronegativity and resonance Acid pKa Conjugate Base

Approximate pKa chart of the functional groups: values to know ... H 43

2010年6月18日 · Not knowing pKa values in organic chemistry is like not knowing the value of the hands in poker. In this scheme, alkyl anions are the equivalent of the royal flush – they win the proton from everything underneath them in the table. Why is pK a so important? Because every nucleophile is potentially a base, and vice versa.

Equilibrium pKa Table (H2O Solvent) Values outside the boxes were determined by approximate methods

2023年4月2日 · A general rule is that a good leaving group is STABLE, the more stable it is, the easier it is for the leaving group to leave. A measure of stability of the leaving group is to look at the pKa of its conjugate acid. If the conjugate acid is a STRONG acid, then the leaving group is a weak (stable) base and therefor a GOOD leaving group.

CH3OH ＞ 1 醇 醇 醇 取代酚的酸性影响因数： 酚羟基的邻、对位上有强吸电子时，酸 性增强，吸电子基越多，酸性越强； 酚羟基的邻、对位上有给电子时，酸性 减弱。 此法主要用于硝基酚和氯代酚的生产。 (3) 碱熔法制备酚. 此法曾是工业制酚的主要方法. f多元醇的命名： ——写出多个羟基所在位置。 HOCH2CHCH3 HOCH2CH2CH2OH OH 1,3-丙二醇 1,2-丙二醇 (2) 酚的命名 酚的俗名： 9.6.2 醚的生成 醇的酸性太弱，不能与卤代烃反应生成 醚。 醇、酚的金属盐与卤代烃作用， …