Oral suspension in multidose vial, to be administered on the tongue, with dropper; Dosage and vaccination schedule. One dose = 2 drops (approximately 0.1 ml) In endemic areas or areas at risk of poliovirus importation, according to WHO recommendations. Child: 4 doses approximately 4 weeks apart, at birth then at 6, 10 and 14 weeks of age

2020年11月3日 · nOPV2 is a genetically modified version of the existing OPV type 2 that, based on currently available data, provides comparable protection against poliovirus type 2 while being more genetically stable.

OPV type 2 vaccine, or mOPV2) that provides comparable protection against poliovirus type 2. The vaccine is more genetically stable than OPV2, which makes it less likely to

2023年4月6日 · Following the switch, monovalent type 2 OPV (mOPV2) has been put into use in response to detected circulating vaccine-derived type 2 polioviruses outbreaks (cVPDV2). Currently, any case or isolate of VDPV2 is considered a potential global public health threat that requires a rapid, coordinated response involving the Global Polio Eradication ...

All the vials of OPV have a temperature sensitive label, the vaccine vial monitor (VVM), attached at the time of manufacture, to prominently display the cumulative exposure to heat. It is a standard practice to discard vials when VVM colour changes to grey from white suggesting that the potency of the vaccine has dropped to >0.6 log10 1 .

OPV is a clear red or yellow liquid vaccine that may come in either of two types of containers: Small plastic bottles that work like droppers – the drops are given directly from the dropper into the baby’s mouth. Glass vials with a dropper (also made of glass) supplied in a separate plastic bag. Remove the metal or plastic cap from the vial of OPV.

A vaccine vial monitor (VVM) which measures cumulative exposure to heat, is a temperature-sensitive label attached to each vial of the vaccine at the time of manufacture. The VVM is a label made of a heat-sensitive, long-chain polymer with a static, temperature-insensitive ref erence colour printed as a circle sur rounding this heat-sensitive ...

Oral polio vaccine (OPV), a prototypical mucosal vaccine, demonstrates the key advantages and challenges of mucosal vaccination. The ease of delivery of OPV drops enables minimally trained volunteers to distribute the OPV drops in house-to-house campaigns that have been essential for the current successes of the global polio eradication effort.

2010年4月26日 · We conducted the first systematic documentation of using oral polio vaccine (OPV) out of the cold chain during national immunization day (NID) campaigns in Mali. Using a crossover intervention design, vaccinators compared the transport of OPV in vaccine carriers with or without ice packs.

Oral polio vaccine is the most heat sensitive of all vaccines used in the Expamded Programme on Immunization (EPI). Storage and transport have to comply with good cold chain practices. However, cumulative heat exposure can now be monitored with the help of the vaccine vial monitor (VVM),1 which can be found on all OPV supplied by UNICEF since 1997.