2025年2月12日 · Osmotic demyelination syndrome is the preferred term, replacing central pontine myelinolysis, recognizing that extrapontine structures can also be affected, previously known as extrapontine myelinolysis. Osmotic demyelination syndrome usually occurs in the setting of rapidly corrected electrolyte disturbance 1,8:

2022年12月20日 · 概述渗透性脱髓鞘综合征(osmotic demyelination syndrome, ODS)是一种发生在中枢神经系统的急性非炎性脱髓鞘疾病，以神经髓鞘破坏为特征 ， 一般认为与脑内渗透压平衡失调有

The diagnostic modality of choice is magnetic resonance imaging (MRI) of the brain, which can also be used to detect oligosymptomatic ODS. The current mainstay of management is prevention; treatment strategies for manifest ODS are still experimental.

A short-term follow-up brain magnetic resonance imaging (MRI) eventually revealed ODS. Initially, the findings of ODS were masked due to symptoms of alcohol withdrawal. However, the patient had a quick recovery with the improvement of all the neurological findings.

2017年2月14日 · 渗透性脱髓鞘综合征（osmotic demyelination syndrome，ODS）是一种少见的急性非炎症性中枢脱髓鞘性疾病。 1959 年 Adams 首次对该病进行报道，仅发现在脑桥中央的髓鞘溶解，遂命名为脑桥中央髓鞘溶解症（central pontine myelinolysis，CPM）。 其后人们发现该病变也可累及脑桥外的其他部位，如基底节、丘脑等（约占 10%），称之为脑桥外髓鞘溶解症（extrapontine myelinolysis，EPM）。 CPM 和 EPM 二者可以单独发生，也可以合并出现，遂 …

Osmotic Demyelination Syndrome (ODS) is a condition seen due to the loss of normal myelin in the central nervous system. Multiple etiologies have been identified as causing this condition, however, the most reported cause is the rapid correction of hyponatraemia.

With the introduction of magnetic resonance imaging (MRI), the incidence of ODS has increased, and some patients have few symptoms or no symptoms. Currently, for suspected patients, a complete medical history and imaging findings are largely used to determine an ODS diagnosis.

2014年4月1日 · Osmotic demyelination syndrome (ODS) refers to central pontine myelinolysis and extrapontine myelinolysis. These disorders are characterized by insults to regions of the brain with anatomical features predisposing white matter tracts to myelin injury in the setting of osmotic disturbances and their attempted correction.

A 70-year-old man who suffered from osmotic demyelination syndrome (ODS) is presented. Dyspnea, pseudobulbar palsy and motor weakness were seen. MRI in the acute stage revealed focal abnormal high-signal lesions in the pons, thalamus and bilateral cortical areas on T1-weighted and FLAIR images.

2013年8月1日 · MRI is decisive in making a diagnosis of ODS, helping to uncover new cases, delineate the extent of and trace evolution of the lesion, and correlate progression or regression with clinical features [8].