
Naphthalene, a versatile platform in medicinal chemistry: Sky-high ...
2019年1月1日 · Thus, the naphthalene scaffold emerges as an important building block in drug discovery owing to its broad spectrum of biological activities through varying structural modifications. This review incorporates the pharmacological aspects of different types of chemically modified naphthalene-based molecules along with their activity profile.
Naphthalene - an overview | ScienceDirect Topics
Naphthalene, the simplest bicyclic aromatic ring, is conventionally derived from coal tar. It is a white solid material with strong pungent odour. Naphthalene was first discovered by Scottish chemist, Alexzander garden in 1819. Michael Faraday first reported its molecular formula (C 10 H 8) in 1826 [1]. Conventionally, naphthalene is ...
Naphthalene - an overview | ScienceDirect Topics
Naphthalene (91-20-3) is a component of crude oil and is found in petroleum-derived fuels and consumer products. The most common use of naphthalene in consumer products is in the production of mothballs. Naphthalene ingestion can result in acute as well as delayed toxicity. The primary target organs of toxicity are the blood and the eyes.
Naphthalene: Risk assessment and environmental health hazard
2025年1月1日 · Naphthalene is a two fused benzene ring polycyclic aromatic hydrocarbon. Naphthalene was initially registered with the U.S. Department of Agriculture (USDA) as a pesticide in 1948. The United States Environmental Protection Agency (EPA) issued a registration standard for naphthalene in 1981, and the substance was reregistered by the agency in 2008.
Naphthalene - an overview | ScienceDirect Topics
2011年2月3日 · Naphthalene conversion (naphthalene hydrogenated to tetralin, octalins and decalins) varied from 4 to 96%. This corresponds to a naphthalene hydrogenation rate of 1-24×10 3 mol/(kg cat s). An additional experiment carried out with very low catalyst loading led to a low naphthalene conversion and only tetralin as product.
Naphthalene - an overview | ScienceDirect Topics
Naphthalene. Naphthalene is the most volatile polyaromatic hydrocarbon. The migration of its vapors from creosote-contaminated groundwater to surface soil poses a risk at the former railroad tie operation site at Oneida, Tennessee [21].
Naphthalene, a versatile platform in medicinal chemistry: Sky-high ...
2019年1月1日 · Naphthalene, an organic compound with formula C 10 H 8, is also known as naphthene, naphthalin, camphor tar, and white tar. It is an essential compound of coal tar [27]. The structure of naphthalene consists of a fused pair of benzene rings. It is the simplest polycyclic aromatic hydrocarbon and is a white crystalline solid.
Naphthalene - an overview | ScienceDirect Topics
The toxic nature of naphthalene is believed to be due to oxidative stress since naphthalene is metabolised to 1,2-naphthalene oxide which depletes GSH pools by S-conjugation (Wells et al., 1989). The lens is not able to directly form naphthalene 1,2-oxide from naphthalene, and naphthalene itself is incapable of cataract induction in cultured ...
Mechanism for the catalytic thermal polycondensation of …
2022年10月1日 · Compared with naphthalene and 1,1'-binaphthalene, the naphthalene polymers N-10-150-0.5 and N-10-150-8 display obviously weaker peaks at 781 cm–1, indicating that the proportion of naphthalene rings in the naphthalene polymer is greatly reduced and the PAHs with higher degree of aromatization are formed.
Highly selective production of 2-methylnaphthalene by CO
2024年12月1日 · In this study, CO 2 hydrogenation was coupled with naphthalene alkylation, and the H 3 CO* active intermediate generated in situ was alkylated with naphthalene by using metal oxide-zeolite (OX-ZEO) bifunctional catalysts, which exhibited the ‘slow release’ phenomenon of the methylation reagent. It improved naphthalene conversion, suppressed ...