A nanogel is a polymer-based, crosslinked hydrogel particle on the sub-micron scale. [1] [2] [3] These complex networks of polymers present a unique opportunity in the field of drug delivery at the intersection of nanoparticles and hydrogel synthesis.

Nanogels possess properties of both hydrogels and nanoparticles and can be categorized into nanohydrogels and nano-organogels. These systems exhibit exceptional drug-loading capability, stability, biological consistency, and environmental responsiveness.

Nanogels are three-dimensional hydrogel materials in the nanoscale size range formed by crosslinked swellable polymer networks with a high capacity to hold water, without actually dissolving into the aqueous medium. Nanogels can be composed of a variety of naturally occurring polymers, synthetic polymers or a combination thereof.

2019年4月18日 · Nanogels and microgels are soft, deformable, and penetrable objects with an internal gel-like structure that is swollen by the dispersing solvent.

2023年10月1日 · Nanogels, also termed hydrogel nanoparticles, have the properties and functions of both nanomaterials and hydrogels. Till date, a considerable number …

Nanogels, a type of systemic drug delivery carrier, are hydrogels with a three-dimensional (3D) tunable porous structure and a particle size in the submicrometer range, from 20 to 250 nm; nanogels can be discriminated from microgels, which have a particle size ranging from 1 to 350 µm, and in situ-forming hydrogels, which facilitate local delive...

2021年3月29日 · Nanogels (NGs) can be defined as submicron-sized hydrogels, formed by physically or chemically crosslinked polymeric chains which give rise to a three-dimensional (3D) tunable porous network with a high capacity to absorb water, without actually dissolving into an aqueous medium [7].

2021年9月5日 · Nanogels in biomedical field are promising and innovative materials as dispersions of hydrogel nanoparticles based on crosslinked polymeric networks that have been called as next generation drug delivery systems due to their relatively high drug encapsulation capacity, uniformity, tunable size, ease of preparation, minimal toxicity, stability in...

2024年1月14日 · Nanogels have considerable potential in bioactive substance delivery, organ targeting, and chemotherapy. The article highlighted the preparation, types, evaluation and applicability of...

2021年7月11日 · Nanogel is nanoparticles made up of a strongly cross-linking hydrogel that may response to a wide scale of environmental stimuli. Nanogel can be produced on the same dimension as biological cell and sub-cellular systems.