NPM1 - Wikipedia
NPM1 shows characteristic properties of molecular chaperones such as a) preventing temperature dependent and independent aggregation of proteins, b) preserving enzyme …
NPM1 Gene - GeneCards | NPM Protein | NPM Antibody
2025年3月30日 · NPM1 (Nucleophosmin 1) is a Protein Coding gene. Diseases associated with NPM1 include Acute Myeloid Leukemia With Multilineage Dysplasia and Lymphomatoid …
Significance of NPM1 Gene Mutations in AML - PMC
The aim of this literature review is to examine the significance of the nucleophosmin 1 (NPM1) gene in acute myeloid leukaemia (AML). This will include analysis of the structure and normal …
JHO：曹雪涛团队揭示癌症免疫治疗新靶点——NPM1_腾讯新闻
2024年11月25日 · 提示了NPM1是改善肿瘤免疫治疗的潜在靶点。 核磷蛋白（NPM1）是最丰富的核仁蛋白之一，NPM1基因的突变与多种血液系统恶性肿瘤相关，包括急性髓系 ...
Functions of the native NPM1 protein and its leukemic mutant
2024年12月17日 · Thanks to its property to act as histone chaperone and to shuttle between the nucleus and cytoplasm, the NPM1 protein is involved in multiple cellular function that are here …
Current status and future perspectives in targeted therapy of NPM1 ...
2022年8月25日 · NPM1 mutations are the most common genetic alteration in acute myeloid leukemia (AML), detected in about 30–35% of adult AML and more than 50% of AML with …
发现 NPM1 突变蛋白诱导急性髓系白血病新机制，计划开发小分 …
NPM1 蛋白是一种广泛在细胞核仁表达且高度保守的磷酸化蛋白，参与核糖体蛋白的组装和运输，调控中心体的复制以及癌症抑制因子 ARF 的表达。
Nucleophosmin: from structure and function to disease …
2016年8月24日 · Nucleophosmin (NPM1), also known as B23, No38 or Numatrin, is an abundant nucleolar protein found in the nuclei of proliferating cells. NPM1 has been documented as …
JHO：曹雪涛团队揭示癌症免疫治疗新靶点——NPM1_澎湃号·湃 …
2024年11月25日 · 核磷蛋白（NPM1）是最丰富的核仁蛋白之一，NPM1基因的突变与多种血液系统恶性肿瘤相关，包括急性髓系白血病（AML）。 有研究表明，NPM1通过促进细胞增殖和抑 …
核磷蛋白 1（NPM1）基因 | MCE
该基因编码的蛋白质参与多种细胞过程，包括中心体复制、蛋白质伴侣和细胞增殖。 编码的磷蛋白在核仁、细胞核和细胞质之间穿梭，陪伴核糖体蛋白和核心组蛋白从细胞核到细胞质。 还已 …