NOD2 - Wikipedia
NOD2 is an intracellular pattern recognition receptor, which is similar in structure to resistant proteins of plants and recognizes molecules containing the specific structure called muramyl …
NOD2基因敲除小鼠与炎性肠道疾病 - 知乎
NOD2 （Nucleotide-binding oligomerization domain 2）也被称为NLRC2，属于NLR家族，是革兰氏阳性和革兰氏阴性细菌的肽聚糖（PGN）衍生的细胞内 模式识别受体 （PRRs）。 NOD2 …
NOD2, an intracellular innate immune sensor involved in host …
2011年7月13日 · NOD2 (nucleotide-binding oligomerization domain 2) is a member of the NLR (NOD, leucine-rich repeat (LRR)-containing protein) family of intracellular sensors of …
NOD2 gene: MedlinePlus Genetics
The NOD2 gene (previously known as CARD15) provides instructions for making a protein that plays an important role in immune system function. The NOD2 protein is active in some types …
NOD1 and NOD2: Signaling, Host Defense, and Inflammatory Disease
The nucleotide-binding oligomerization domain (NOD) proteins, NOD1 and NOD2, the founding members of the intracellular NOD-like receptor family, sense conserved motifs in bacterial …
NOD2 and inflammation: current insights - PMC
The nucleotide-binding oligomerization domain (NOD) protein, NOD2, belonging to the intracellular NOD-like receptor family, detects conserved motifs in bacterial peptidoglycan and …
Nature | 克罗恩病最大遗传因素: 细菌成分感受器NOD2突变 - 知乎
NOD2是一种胞内受体 (图1)，可以识别分子胞壁二肽 (MDP)——细菌细胞壁中普遍存在的成分。 细胞中NOD2的激活导致了称为细胞因子的炎症分子的表达，而异常强烈的炎症反应可以介导 …
NOD2 Gene - GeneCards | NOD2 Protein | NOD2 Antibody
2025年3月30日 · NOD2 (Nucleotide Binding Oligomerization Domain Containing 2) is a Protein Coding gene. Diseases associated with NOD2 include Blau Syndrome and Inflammatory …
Nature：nod2基因缺陷抑制肠道纤维化和炎症的有效恢复，导致克罗恩病…
2021年4月27日 · NOD2是一种胞内受体，可识别分子胞壁二肽 (MDP)——细菌细胞壁中普遍存在的成分。 在NOD2被描述为克罗恩病的风险基因之前，NOD2的功能在 免疫 细胞中得到了最 …
含核苷酸结合寡聚化结构域 2（NOD2）基因 | MCE
它通过识别源自它们的胞壁酰二肽 (MDP) 并激活 NFKB 蛋白，在对细胞内细菌脂多糖 (LPS) 的免疫反应中发挥作用。 该基因的突变与克罗恩病和布劳综合征有关。 已发现该基因编码不同亚 …