2010年1月27日 · Here we report our discovery that the ND6 gene and tRNAGlu were not lost but had been translocated to the control region (CR) from their canonical location between ND5 …

The complementary L-strand serves as a template for the production of only 1 mitochondrial messenger RNA (mt-mRNA) that encodes subunit 6 of NADH dehydrogenase (ND6), 8 mt …

MT-ND6 is a gene of the mitochondrial genome coding for the NADH-ubiquinone oxidoreductase chain 6 protein (ND6). [5] The ND6 protein is a subunit of NADH dehydrogenase (ubiquinone), …

2023年8月3日 · We demonstrated that allotopic expression of nucleus-versions of ND6 restored complex I, apoptosis and mitophagy deficiencies caused by the m.14484T > C mutation. The …

In this work, we devised the mitochondrial dimethyl sulfate mutational profiling with sequencing (mitoDMS-MaPseq) method and applied detection of RNA folding ensembles using …

2025年3月29日 · Genetic analysis of mitochondrial DNA (mtDNA) revealed a novel variant of the gene encoding the NADH dehydrogenase subunit 6 (ND6) protein in the tumor tissue. The …

Recently, the mitochondrial (mt) NADH dehydrogenase subunit 6 (ND6) gene and the adjacent transfer RNA Glu (tRNA Glu ) were also reportedly lost. ND6 protein is crucial for the assembly …

Enables NADH dehydrogenase (ubiquinone) activity. Involved in mitochondrial electron transport, NADH to ubiquinone and mitochondrial respiratory chain complex I assembly. Predicted to be …

Mito-mice Nd6 were homoplasmic for the mutation and displayed a mild reduction of CI + III activity in multiple tissues (about 20–30%). Young mice looked healthy and showed only a …

Here we report our discovery that the ND6 gene and tRNA(Glu) were not lost but had been translocated to the control region (CR) from their canonical location between ND5 and …