2024年2月6日 · Our findings have proven that morin significantly induces apoptosis by increasing the levels of apoptotic protein via the generation of ROS. It also effectively reduced inflammatory cytokine levels, thereby exerting anticancer activity against glioma cells.

2024年7月3日 · Morin alleviated diabetic-induced cardiac hypertrophy, fibrosis, and hypertension and improved glycemic and lipid profiles. The suppression of apoptosis may contribute to the alleviation of diabetic-induced cardiomyopathy. Morin was able to promote autophagy and reduce inflammation and oxidative stress in the cardiac tissue. Data Sharing Statement

2024年12月27日 · However, the effect of morin on diabetic cardiomyopathy and its association with autophagy, apoptosis, inflammation, and oxidative stress remains unclear. The current study aimed to reveal the mechanisms underlying morin-mediated protection against cardiac failure in …

2025年1月27日 · Our investigation demonstrates that Morin effectively reverses the decline in growth performance and repairs damaged jejunal structures and barrier function under DON exposure. Furthermore, the proliferation and differentiation of intestinal stem cells (ISCs) is enhanced significantly after Morin intervention.

2016年12月1日 · Our results showed that morin inhibited HG-induced MC proliferation, arrested HG-induced cell-cycle progression, reversed HG-inhibited expression of p21 Waf1/Cip1 and p27 Kip1. It also inhibited HG-induced ECM expression, ROS generation and NOX4 expression in MCs. Furthermore, morin suppressed HG-induced phosphorylation of p38 MAPK and JNK1/2 ...

2025年3月25日 · This study found that Morin effectively reduces the severity of atherosclerotic plaques in ApoE −/− mice. A previous study indicated that Morin could serve as a therapeutic agent for vascular inflammation by promoting the increase of PTEN to inhibit doxorubicin-induced inflammation [2].

2024年11月1日 · Morin is a bioflavonoid mainly extracted from white mulberry, a traditional Chinese herbal medicine with anti-inflammatory and antioxidant properties. This study examines whether morin can alleviate atherosclerosis by suppressing EndMT and seeks to elucidate the underlying mechanism.

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2 天之前 · Various contributions have been reported concerning the inclusion of flavonoids in cyclodextrins (CDs). The association constant ( $${K}_{ass}$$ K ass ) is one fundamental aspect for characterizing inclusion compounds. Distinct association constants were obtained depending on the experimental technique or the pH for flavonoids included in CD. In the present study, we applied two recently ...

Yu Z, Fong WP, Cheng CH: Morin (3,5,7,2',4'-pentahydroxyflavone) exhibits potent inhibitory actions on urate transport by the human urate anion transporter (hURAT1) expressed in human embryonic kidney cells.