Metal-organic frameworks functionalized with nucleic acids …
2022年1月15日 · In this review, we demonstrate the progress of MOF biofunctionalization with nucleic acid- (ssDNA, ds DNA, and aptamer) and amino acid-based biomolecules (single …
Metal-organic frameworks for precise inclusion of single-stranded DNA ...
2018年4月3日 · Here, we design a series of four isoreticular metal-organic frameworks (Ni-IRMOF-74-II to -V) with progressively tuned pore size from 2.2 to 4.2 nm to precisely include …
DNA-Functionalized Metal–Organic Framework Nanoparticles for ...
2019年1月23日 · Based upon the observation that clustered oligonucleotides can naturally engage scavenger receptors that facilitate cellular transfection, nucleic acid–metal organic …
Bio Mater. | MOF在生物技术方面的应用 - 知乎 - 知乎专栏
使用 TFO 探针结合荧光MOF生物传感器检测ds-DNA(来源：ACS Appl. Bio Mater.)。 Wei及其同事设计了一种基于H2dtoaCu-MOF的荧光生物传感器，用于检测H5N1抗体。使用5'6-FAM标记 …
Colloidal crystal engineering with metal–organic framework ...
2020年5月19日 · Here, we show that metal–organic framework nanoparticles (MOF NPs) densely functionalized with oligonucleotides can be programmed to crystallize into a diverse set of …
Nucleic acids biosensors based on metal-organic framework (MOF…
2019年9月15日 · Iron-based MIL-88B MOF nanorods (Tian et al., 2015) have been used as a high-efficient sensing platform for fluorescence DNA detection, with LOD up to 10 pM, and the …
【Anal. Chem.】江苏大学张祯团队：基于MOF核酸相互作用的DNA …
近日，江苏大学张祯教授团队在Analytical Chemistry杂志上发表了题为“Insight into the Sensing Behavior of DNA Probes Based on MOF–Nucleic Acid Interaction for Bioanalysis”的研究论文 …
金属-有机骨架介导的功能核酸检测技术研究进展
MOFs中的有机配体通常含有共轭π-电子系统，允许通过π-π相互作用与单链DNA（ssDNA）结合，这种机制类似于氧化石墨烯（GO）和生物分子之间的相互作用 [8]。 如今，MOFs已被广泛 …
Metal–organic framework-based smart stimuli-responsive drug …
2025年2月28日 · When ATP-sensitive DNA-modified MOF systems come into contact with ATP-enriched culture medium, ATP interacts with the ATP-sensitive DNA, leading to the unlocking …
Porphyrin-based metal–organic frameworks in drug delivery for …
14 小时之前 · The possibility of imaging in porphyrin-based MOF leads to real-time monitoring of treatment results and personalization of treatment strategies. ... breast cancer , and …