Mitotane, sold under the brand name Lysodren, is a steroidogenesis inhibitor and cytostatic antineoplastic medication which is used in the treatment of adrenocortical carcinoma and Cushing's syndrome.

2025年3月3日 · Mitotane is used to treat cancer of the adrenal gland (adrenal cortical carcinoma). Mitotane may also be used for purposes not listed in this medication guide. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Mitotane may cause serious side effects.

米托坦（Lysodren，mitotane）于1970年获得美国食品药品监督管理局（FDA）批准用于治疗肾上腺皮质癌，并于2004年被欧洲药品管理局（EMA）列为罕见病药物。米托坦（Lysodren，mitotane）原由美国施贵宝公司（Bristo…

Despite the pivotal role of mitotane in adrenocortical carcinoma (ACC) management, data on the endocrine toxicities of this treatment are lacking. The aim of this systematic review is to collect the available evidence on the side effects of mitotane on the endocrine and metabolic systems in both children and adults affected by adrenal carcinoma.

Mitotane is used to treat cancer of the adrenal glands (adrenocortical carcinoma) that cannot be removed by surgery. This medicine acts on a part of the body called the adrenal cortex. Mitotane reduces the amount of steroids (cortisone-like hormones) that are produced by the adrenal cortex.

Mitotane is an adrenal cortex inhibitor used to treat adrenocortical tumors and Cushing's syndrome. Mitotane is an adrenolytic isomer of the insecticide dichlorodiphenyldichloroethane (DDD) - itself a metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and their production of hormones.

Mitotane is used to treat cancer of the adrenal gland that can not be treated with surgery. Mitotane is in a class of medications called antineoplastic agents. It works by slowing growth or reducing the size of the tumor. How should this medicine be used? Mitotane comes as …

肾上腺皮质癌(ACC)是一种罕见的侵袭性肾上腺癌，迄今为止，批准用于治疗ACC的药物仅有唯一一个：米托坦(Mitotane，Lysodren®)。 目前已在国内获批上市，但尚未开始销售，价格尚未公布（截止2024年6月份）。

2019年1月7日 · 肾上腺癌唯一的克星米托坦（mitotane） 万邦行健国际医药 2019-01-07. 肾上腺皮质癌(Adrenocortical carcinoma，ACC)是罕见的内分泌恶性肿瘤，预后较差。手术完全切除是目前首选治疗方法,手术方式包括开放性肾上腺切除术和腹腔镜肾上腺切除术。

Mitotane is also known as Lysodren®. It is used to treat a rare cancer of the adrenal glands called adrenal cortical carcinoma.