Structure and function of mitochondrial membrane protein …
2015年10月29日 · Biological energy conversion in mitochondria is carried out by the membrane protein complexes of the respiratory chain and the mitochondrial ATP synthase in the inner membrane cristae. Recent advances in electron cryomicroscopy have made possible new insights into the structural and functional arrangement of these complexes in the membrane, and ...
Inner mitochondrial membrane - Wikipedia
The inner mitochondrial membrane is both an electrical insulator and chemical barrier. Sophisticated ion transporters exist to allow specific molecules to cross this barrier. There are several antiport systems embedded in the inner membrane, allowing exchange of anions between the cytosol and the mitochondrial matrix.
Protein insertion into the inner membrane of mitochondria: …
2024年4月25日 · The inner membrane of mitochondria contains hundreds of different integral membrane proteins. These proteins transport molecules into and out of the matrix, they carry out multifold catalytic reactions and they promote the biogenesis or degradation of …
Mitochondrial proteins: from biogenesis to functional networks
2019年1月9日 · The respiratory chain complexes of the mitochondrial inner membrane are the core of a large protein network that connects bioenergetics to mitochondrial biogenesis, regulation and...
Mitochondria - The Cell - NCBI Bookshelf - National Center for ...
In contrast to the inner membrane, the outer mitochondrial membrane is freely permeable to small molecules. This is because it contains proteins called porins, which form channels that allow the free diffusion of molecules smaller than about 6000 daltons.
The mitochondrial inner membrane protein LETM1 modulates …
2020年3月5日 · LETM1 is a mitochondrial inner membrane protein that is required for maintaining the mitochondrial morphology and cristae structures, and regulates mitochondrial ion homeostasis. Here we...
The cell biology of mitochondrial membrane dynamics
2020年2月18日 · The twofold role of mitochondria as cellular powerhouses and signalling organelles is paralleled by the fact that they are surrounded by two membranes: an inner mitochondrial membrane (IMM)...
Structure of the mitochondrial inner membrane AAA+ protease …
2017年11月3日 · We present an atomic model of a substrate-bound inner mitochondrial membrane AAA+ quality control protease in yeast, YME1. Our ~3.4-angstrom cryo–electron microscopy structure reveals how the adenosine triphosphatases (ATPases) form a closed spiral staircase encircling an unfolded substrate, directing it toward the flat, symmetric protease ring.
Protein insertion into the inner membrane of mitochondria
The inner membrane of mitochondria contains hundreds of different integral membrane proteins. These proteins transport molecules into and out of the matrix, they carry out multifold catalytic reactions and they promote the biogenesis or degradation of mitochondrial constituents.
The Transport of Proteins into Mitochondria and Chloroplasts
The TIM22 complex mediates the insertion of a subclass of inner membrane proteins, including the carrier protein that transports ADP, ATP, and phosphate. A third protein translocator in the inner mitochondrial membrane, the OXA complex, mediates the insertion of inner membrane proteins that are synthesized within the mitochondria. It also helps ...
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