Our narrative review demonstrates that metoclopramide should be used more frequently as the first-line therapy for acute migraine headaches over opioids, with more studies needed to be …

Migraine is a common episodic disorder, the hallmark of which is a disabling headache generally associated with nausea and/or light and sound sensitivity. The acute treatment of migraine in …

Randomized, placebo-controlled evaluation of prochlorperazine versus metoclopramide for emergency department treatment of migraine headache. Ann Emerg Med. …

Metoclopramide is efficacious in the treatment of both the pain and nausea of migraine headache. This is a direct action that is not dependent on the concomitant administration of another agent.

2002年12月1日 · While metoclopramide (Reglan) is sometimes recommended as a single agent in the treatment of migraine pain, its main use is for treating accompanying nausea and …

2018年4月30日 · Diphenhydramine doesn’t work for headaches [208 patient RCT, REF]. Diphenhydramine doesn’t prevent metoclopramide-associated akathisia [REF; REF] (which in …

2023年6月8日 · A dose of 10 mg of metoclopramide was effective in reducing acute migraine attacks, it only showed a lower significant effect compared with granisetron regarding …

2005年5月1日 · Compared with placebo in five small studies enrolling 185 patients, metoclopramide produced significant reductions in headache pain, although the effect was not …

2011年2月1日 · Intravenous metoclopramide (Reglan) is effective for acute migraine treatment. Parenteral dexamethasone is useful as an adjunctive treatment in the emergency department …

2023年6月8日 · A dose of 10 mg IV Metoclopramide was effective in relieving migraine attacks with minimal side effects. Compared to other active drugs, it only showed a lower significant …