Mesna, sold under the brand name Mesnex among others, is a medication used in those taking cyclophosphamide or ifosfamide to decrease the risk of bleeding from the bladder. [1] It is used either by mouth or injection into a vein. [1] Common side effects include headache, vomiting, sleepiness, loss of appetite, cough, rash, and joint pain. [1]

2025年1月21日 · What is mesna? Mesna is used to prevent bleeding in the bladder (hemorrhagic cystitis) during chemotherapy with ifosfamide . Mesna will not prevent other side effects caused by ifosfamide. Mesna may also be used for purposes not listed in this medication guide.

2025年3月17日 · Mesna Injection is a sterile, nonpyrogenic, aqueous solution of colorless to light pink appearance in clear glass multidose vials for intravenous administration. Mesna Injection contains 100 mg per mL mesna, 0.25 mg per mL edetate disodium, sodium hydroxide for pH adjustment and qs with Water for Injection.

Mesna is a drug given with some types of chemotherapy to help protect the bladder from irritation. The chemotherapy drugs ifosfamide and cyclophosphamide can sometimes irritate the lining of the bladder. This can cause bleeding from the bladder and may show up as blood in your urine (pee). This is called haematuria.

2025年2月18日 · Mesna is commonly used to reduce the risk of bladder inflammation and bleeding (hemorrhagic cystitis) that can happen after using the chemotherapy medicine, ifosfamide.

Mesna is used to reduce the risk of hemorrhagic cystitis (a condition that causes inflammation of the bladder and can result in serious bleeding) in people who receive ifosfamide (a medication used for the treatment of cancer). Mesna is in a class of medications called cytoprotectants.

Mesna is a synthetic compound that protects the bladder from the urotoxic metabolites of oxazaphosphorine derivatives (e.g., ifosfamide, cyclophosphamide) by chemically interacting with them and their metabolites as a

2025年1月21日 · Detailed Mesna dosage information for adults and children. Includes dosages for Hemorrhagic Cystitis Prophylaxis; plus renal, liver and dialysis adjustments.

2020年2月17日 · Includes Mesna indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more.

2024年10月9日 · Mesna (Mesnex) is used to prevent hemorrhagic cystitis (bleeding in the bladder) in people receiving a chemotherapy medication called ifosfamide (Ifex). It's sometimes used off-label in people receiving cyclophosphamide. Mesna (Mesnex) is given as three separate doses, about 2 to 4 hours apart, on the same day as the chemotherapy.