Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B). They are best known as effective antidepressants, especially for treatment-resistant depression and atypical depression. [1] .

2024年11月22日 · Monoamine oxidase inhibitors (also called MAO inhibitors or MAOIs) block the actions of monoamine oxidase enzymes. Monoamine oxidase enzymes are responsible for breaking down neurotransmitters such as dopamine, norepinephrine, and serotonin in the brain.

2021年7月29日 · There are two main types of monoamine oxidases: MAO-A and MAO-B. Both types break down the following neurotransmitters: MAO-A is most involved in breaking down serotonin. As MAOIs block...

2024年6月5日 · MAOIs are a type of antidepressant. They inhibit monoamine oxidase, increasing levels of neurotransmitters in the brain. Learn about MAOIs safety here.

2023年7月17日 · The monoamine oxidase enzyme breaks down different types of neurotransmitters from the brain: norepinephrine, serotonin, dopamine, and tyramine. MAOIs inhibit the breakdown of these neurotransmitters thus, increasing their levels and allowing them to continue to influence the cells that have been affected by depression. [6]

2025年2月27日 · Monoamine oxidase inhibitors, also called MAOIs, were the first type of antidepressant developed. They're effective, but they've generally been replaced by antidepressants that are safer and cause fewer side effects. If you take an MAOI, you may need to stay away from certain foods and medicines.

2023年8月30日 · What are the types of MAOIs? MAOIs (and their brand names) that healthcare providers can currently prescribe in the United States include: Isocarboxazid (Marplan®). Phenelzine (Nardil®). Selegiline (Emsam®). Tranylcypromine (Parnate®). What conditions do MAOIs help treat?

2023年4月13日 · Monoamine oxidase inhibitors (MAOIs) are medications for depression. They take time to work but can be helpful along with other therapies and lifestyle changes. However, they...

2014年8月19日 · There are two common subtypes of monoamine oxidase inhibitors, MAO-A inhibitors and MAO-B inhibitors. MAO-A: The MAO-A subtype specifically focuses on tyramine, serotonin, norepinephrine, and dopamine. MAO-B: The MAO-B subtype focuses more on dopamine, phenylethylamine and trace amines.

2024年3月21日 · Monoamine oxidase inhibitors (MAOIs) are a type of antidepressant medication that was first developed and used in the 1950s. Today, they are not commonly prescribed as a first-line treatment, as they require dietary restrictions, and …