Malate dehydrogenase - Wikipedia
Malate dehydrogenase (EC 1.1.1.37) (MDH) is an enzyme that reversibly catalyzes the oxidation of malate to oxaloacetate using the reduction of NAD + to NADH. This reaction is part of many …
16.2: Reactions of the Citric Acid Cycle - Biology LibreTexts
2024年5月22日 · Malate dehydrogenases are found in the cytoplasm, where it's part of the aspartate-malate shuttle that moves cytoplasmic malate (and through MDH indirectly NADH) …
Catalytic mechanism and kinetics of malate dehydrogenase
2024年10月3日 · Malate dehydrogenase (MDH, EC 1.1.1.37) catalyzes the reversible conversion of L-malate ((S)-malate) to oxaloacetate, accompanied by the conversion of NAD + to NADH + …
Malate Dehydrogenases catalyze the reaction: Malate + NAD + Oxaloacetate + NADH involving a simple hydride transfer from the 2 position of Malate to NAD + to form the reduced
Malate Dehydrogenase: Regulation - University of Wisconsin–Eau …
Malate dehydrogenase is allosterically regulated. The oxidation of malate into oxaloacetate is a reversible reaction. Production of oxaloacetate is stimulated by high concentrations of malate, …
Molecule of the Month: Citric Acid Cycle - RCSB: PDB-101
Instead, the two forms of malate dehydrogenase form part of a shuttle. In the cytoplasm, NADH is used up to convert oxaloacetate to malate. Then, malate is transported into the mitochondrion …
Function, kinetic properties, crystallization, and regulation of ...
Malate dehydrogenase (MDH) is an enzyme widely distributed among living organisms and is a key protein in the central oxidative pathway. It catalyzes the interconversion between malate …
The structural biology and dynamics of malate dehydrogenases
2024年10月3日 · Malate dehydrogenase (MDH) enzymes catalyze the reversible oxidoreduction of malate to oxaloacetate using NAD(P) as a cofactor. This reaction is vital for metabolism and …
Malate dehydrogenase: distribution, function and properties.
1998年9月1日 · Malate dehydrogenase (MDH) (EC 1.1.1.37) catalyzes the conversion of oxaloacetate and malate. This reaction is important in cellular metabolism, and it is coupled …
Structural analysis and reaction mechanism of malate dehydrogenase …
2021年3月16日 · Malate dehydrogenase (MDH) catalyzes the reversible reduction of oxaloacetate (OAA) to L-malate using nicotinamide adenine dinucleotide hydrogen. MDH has two …