Macrolides mainly affect gram-positive cocci and intracellular pathogens such as mycoplasma, chlamydia, and legionella. Erythromycin was the first macrolide discovered; other macrolides …

2025年2月19日 · Macrolide antibiotics successfully treat many different bacterial infections. They’re safe and effective for most people. Macrolides are also a helpful alternative if you …

The first macrolide discovered was erythromycin, which was first used in 1952. Erythromycin was widely used as a substitute to penicillin in cases where patients were allergic to penicillin or …

2020年2月1日 · Review the appropriate monitoring necessary for patients on agents in the macrolide class of antibiotics. Describe interprofessional team strategies for improving the …

What Are Names of Macrolide Drugs? What Are Macrolides and How Do They Work? Macrolides are antibiotics used for infections caused by gram -positive bacteria (streptococcal and …

Because macrolides are active against atypical respiratory pathogens, they are often used empirically for lower respiratory tract infections, but another antibiotic is often necessary to …

Macrolide antibiotics inhibit protein synthesis by targeting the bacterial ribosome. They bind at the nascent peptide exit tunnel and partially occlude it. Thus, macrolides have been viewed as …

2025年1月7日 · Clinicians must remain vigilant to optimize macrolide regimens, balance efficacy with potential toxicities or drug interactions, and uphold stewardship principles for preserving …

Macrolide, class of antibiotics characterized by their large lactone ring structures and by their growth-inhibiting (bacteriostatic) effects on bacteria. The macrolides were first discovered in …

Macrolides should be taken during pregnancy only when the benefits of treatment outweigh the risks. With erythromycin and azithromycin, no harmful effects on the fetus have been observed …