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myc基因是目前研究最多的一类核蛋白类癌基因，包括c—myc、n—myc、l—myc、r—myc 4种。 c-myc 原癌基因是最常见的活化原癌基因之一，c-myc参与调控的癌症占人类所患癌症的20%左 …

Myc is a family of regulator genes and proto-oncogenes that code for transcription factors. The Myc family consists of three related human genes: c-myc (MYC), l-myc (MYCL), and n-myc …

2025年2月7日 · Translational control of MYC by RBM42 represents a potential therapeutic mechanism to diminish MYC oncogene levels, thus reducing tumour growth, metastasis and …

5 天之前 · Furthermore, using RNA-FISH with probes against Pax7, Myod1 and Myc, we observed an ~4-fold increase in the number of Pax7+ cells, and an equivalent increase in …

2025年3月30日 · MYC (MYC Proto-Oncogene, BHLH Transcription Factor) is a Protein Coding gene. Diseases associated with MYC include Burkitt Lymphoma and High-Grade B-Cell …

The 5’ untranslated region (UTR) of c-myc (which is well conserved amongst species) plays a significant role in modulating the steady state levels of the c-myc

Through its targets, MYC coordinates nutrient acquisition to produce ATP and key cellular building blocks that increase cell mass and trigger DNA replication and cell division. In cancer, genetic …

2024年9月16日 · MYC regulates cell apoptosis through two 358 main pathways: BCL-2 (B-cell lymphoma 2) pathway and p53 pathway. MYC 359 inhibits BCL-2 and BCL-XL (BCL2 like 1) …

2024年12月6日 · MYC multimers concentrate the nuclear exosome, a 3’-5’ RNA exonuclease, and its targeting complexes around double-stranded RNA and R-loops, and promote exosome …