CD45.1与CD45.2小鼠的区分与应用 - 知乎专栏
CD45是 白细胞共同抗原 （LCA），表达于所有造血细胞（T细胞、B细胞、粒细胞等），但在红细胞、血小板及非造血组织中不表达。 其胞外结构因 外显子选择性剪接 形成不同亚型（ …
Decoding Human Megakaryocyte Development - ScienceDirect
2021年3月4日 · Here we used single-cell RNA sequencing of human MKs from embryonic yolk sac (YS) and fetal liver (FL) to characterize the transcriptome, cellular heterogeneity, and …
High-throughput enrichment and isolation of megakaryocyte progenitor ...
2021年4月15日 · (A,B) Flow cytometry plots displaying CD45 and CD41 intensity of bone marrow cells stained with MK antibodies in the (A) − TPO and (B) + TPO conditions. Seven distinct …
CD45 expression discriminates waves of embryonic …
We characterized the precise phenotype of embryo megakaryocytes in the liver at gestational day 11.5, identifying them as CD41 ++ CD45-CD9 ++ CD61 + MPL + CD42c + tetraploid cells that …
CD41+/CD45+ cells without acetylcholinesterase activity are
Murine megakaryocytes (MKs) are defined by CD41/CD61 expression and acetylcholinesterase (AChE) activity; however, their stages of differentiation in bone marrow (BM) have not been …
CD41+/CD45+ Cells Without Acetylcholinesterase Activity Are Immature ...
2009年1月2日 · GeneChip and semiquantitative polymerase chain reaction analyses revealed that the Lin − /CD41 + /CD45 + /AChE − MKs are assigned at the stage between the progenitor …
【前沿进展】Immunity丨周波/王前飞/程涛/李玥莹/程辉团队发现 …
2024年3月6日 · 巨核细胞（Megakaryocyte，MK）除了广为人知的负责产生具有凝血、免疫等功能的血小板，也作为造血干细胞（HSC）的重要微环境【1】，并亲自参与免疫反应【2】， …
CD41+/CD45+ Cells Without Acetylcholinesterase ... - Oxford …
2007年1月18日 · In murine lineage-negative (Lin −)/CD45 + BM cells, we found CD41 + MKs without AChE activity (AChE −) except for CD41 ++ MKs with AChE activity (AChE +), in …
多发性骨髓瘤患者骨髓浆细胞 CD45 表达的临床和生物学相关性 …
2004年11月16日 · CD45 最初被表征为白细胞共同抗原，可以在所有造血细胞上找到，并且是 B 和 T 淋巴细胞中抗原介导的信号传导和活化的关键调节剂。 CD45 的表达在 MM 的浆细胞中似乎 …
A subset of megakaryocytes regulates development of …
2024年4月5日 · The existence of Mks via 3 days coculture enhanced the hematopoietic cell emergence derived from E10.5 HEC, the number of CD45 + hematopoietic cells produced in …