MCF 10A was derived from adherent cells in the population. The MCF 10A cell line is a non-tumorigenic epithelial cell line. The cells are positive for epithelial sialomucins, cytokeratins …

The MCF10A human mammary epithelial cell line is a widely used in vitro model for studying normal breast cell function and transformation. However, there is limited knowledge about …

MCF10A is a human mammary epithelial cell line. It is a “normal” cell line that was spontaneously immortalized. Unlike cancer lines, MCF10A grows in medium supplemented with additional …

Immortal human mammary epithelial cell lines. Identification of microsatellite instability and mismatch repair gene mutations in breast cancer cell lines.

MCF10A is a spontaneously immortalized, non-malignant breast cell line obtained from a patient with benign fibrocystic disease [32] and is the founder cell line of a progressively more …

MCF10A cells are instrumental in vitro for elucidating the intricacies of normal mammary epithelial cell functions, encompassing cell-cell adhesion mediated by proteins like E-cadherin, …

Aug 15, 2021 · Because of the establishment of MCF10, the use of its most well-known parental line, MCF10A, has allowed breast cancer researchers to model key aspects of normal and …

Oct 7, 2022 · Comprehensive profiling of ligand-induced perturbation responses of the MCF10A mammary epithelial cell line provides an exhaustive resource for identification of the molecular …

The human normal breast cell line MCF-10A is being widely used as a model in toxicity studies due to its structural similarity to the normal human mammary epithelium.

Jan 4, 2024 · To add to the knowledge of the effects of TP53 and PTEN mutations on the DDR network, we performed RNA-seq and phosphoproteomic profiling of three congenic cell lines …