2025年3月30日 · MAF (MAF BZIP Transcription Factor) is a Protein Coding gene. Diseases associated with MAF include Ayme-Gripp Syndrome and Cataract 21, Multiple Types. Among its related pathways are Gene expression (Transcription) and RUNX2 regulates bone development.

Transcription factor Maf, also known as proto-oncogene c-Maf or V-maf musculoaponeurotic fibrosarcoma oncogene homolog, is a transcription factor that in humans is encoded by the MAF gene. [5] [6]

2023年2月7日 · The traffic-jam, the D. melanogaster ortholog of the large Maf gene, is exclusively expressed in somatic gonadal cells directly adjacent to germline cells. The traffic jam dysfunction leads to improper intermingling of somatic cells with germ cells, resulting in defective differentiation of germ cells.

2025年2月8日 · Transcription Factor c-Maf Promotes Immunoregulation of Programmed Cell Death 1-Expressed CD8 (+) T Cells in Multiple Sclerosis.

The three first exons of the MafG gene are clustered in a relatively compact region, and the 6.8 kb upstream region, which includes these three exons and the 3.3 kb downstream region of this gene, are able to recapitulate endogenous mouse MafG expression in …

2018年11月16日 · The proteins of MAF family (the cellular counterpart of viral oncogene MAF, isolated from avian musculoaponeurotic fibrosarcoma) are transcription factors regulating gene expression. On the bases of the size, they are sub-grouped into two families: the “large” (L-MAFs: MAFA, MAFB, c-MAF, and Nrl) and the “small” (S-MAFs: MAFF, MAFK, and ...

MAF, also known as c-Maf, is a transcription factor that can act as both an activator and repressor of gene expression. It plays a role in lens development, specifically in the differentiation of lens fiber cells. MAF interacts with coactivators CREBBP and …

maf bzip 转录因子： 由该基因编码的蛋白质是一种结合 dna、含有亮氨酸拉链的转录因子，可作为同源二聚体或异源二聚体。 根据结合位点和结合伙伴，编码的蛋白质可以是转录激活因子或抑制因子。

这个基因编码的蛋白质是一个结合DNA的、包含亮氨酸拉链的转录因子，它可以作为同源二聚体或异源二聚体发挥作用。 根据结合位点和结合伙伴的不同，编码的蛋白质可以是转录激活子或抑制子。 这个蛋白质在调节几个细胞过程中发挥重要作用，包括胚胎晶状体纤维细胞发育、T细胞对凋亡的敏感性增加和软骨细胞终末分化。 这个基因的缺陷是导致青少年发作的颗粒性白内障以及先天性蓝绀性白内障4（CCA4）的原因。 已经发现这个基因有两个转录变异体，编码不同的异构体 …

2012年10月1日 · The small MAFs, MAFF, MAFG and MAFK have emerged as crucial regulators of mammalian gene expression. Previous studies have linked small MAF function, by virtue of their heterodimerization with the Cap ‘n’ Collar (CNC) family of transcription factors, to the stress response and detoxification pathways.