Localized scleroderma only affects the skin and the structures directly under the skin. Systemic scleroderma, also called systemic sclerosis, affects many systems in the body. This is the more serious type of scleroderma and can damage your blood vessels and internal organs, such as the heart, lungs, and kidneys.

Localized scleroderma only affects the skin and the structures directly under the skin. Systemic scleroderma, also called systemic sclerosis, affects many parts of the body. This is the more serious type of scleroderma and can damage your blood vessels and internal organs, such as the heart, lungs, and kidneys.

Dermatologists, who specialize in conditions of the skin, hair, and nails, may also play an important role in treating the disease, particularly for people with localized scleroderma. Because scleroderma can affect many different organs and organ systems, you may have several different doctors providing your care.

It is a heterogenous and complex disease that can be categorized as localized scleroderma (morphea) and systemic scleroderma. While etiology of scleroderma is poorly understood, abnormal vasculature, inflammation, and fibrosis are main characteristics of the disease with diverse clinical manifestations (e.g. Raynaud’s phenomenon, digital ...

2025年1月10日 · 45 Other researchers made advances in understanding morphea, or localized scleroderma, by studying pediatric and adult patients. 46 They discovered molecular signatures unique to the disease as well as risk factors for musculoskeletal manifestations in both age groups. Research Into Viruses Elucidates Their Role in SLE

Systemic lupus erythematosus (lupus) is a chronic (long-lasting) autoimmune disease that can affect many parts of the body.

There is no cure for scleroderma, but treatment can improve your quality of life. People with diffuse scleroderma face the most serious long-term outlook if they develop severe kidney, lung, digestive or heart problems. Fortunately, less than one-third of patients with diffuse disease develop these severe problems.

Living with scleroderma. Living with the disease may be hard. To help, try to take an active part in treating your scleroderma. The following tips and suggestions may help. Keep warm. Dress in layers, wear gloves and socks, and avoid cold rooms and weather when possible. Try to avoid cold or wet environments that may trigger symptoms. If you ...

Studies continue to find the genes that predispose a person to getting scleroderma. Those genes may be targets for future therapies. Researchers are also trying to find genes (and other indicators) that could tell doctors who will develop what type of scleroderma. This could someday help doctors identify who might benefit from specific therapies.

Understanding why scleroderma can affect African Americans more severely. Evaluating how immunosuppressant and other medications can be used to help manage the symptoms and complications of scleroderma, particularly pulmonary complications. Exploring the many factors that lead to fibrosis to see if their development can be blocked.