Lobeline is a piperidine alkaloid found in a variety of plants, particularly those in the genus Lobelia, including Indian tobacco (Lobelia inflata), Devil's tobacco (Lobelia tupa), great lobelia …

洛贝林系由山梗菜中提取的生物碱，是一种中枢兴奋药。 本品选择性的刺激颈动脉体化学感受器，反射性地引起呼吸中枢、迷走神经中枢和血管运动中枢的兴奋。 用于新生儿窒息、一氧化 …

Lobeline (α-Lobeline) is a brain-penetrant nicotinic receptor agonist. Lobeline increases dopamine (DA) release by inhibiting DA uptake into synaptic vesicles, and altering presynaptic DA …

(-)-lobeline is an optically active piperidine alkaloid having a 2-oxo-2-phenylethyl substituent at the 2-position and a 2-hydroxy-2-phenylethyl group at the 6-position. It has a role as a nicotinic …

2007年10月21日 · Lobeline inhibits nicotine-evoked dopamine release and [3H]nicotine binding, thus acting as a potent antagonist at both alpha3beta2() and alpha4beta2() neuronal nicotinic …

2025年2月6日 · 半边莲（Lobelia chinensis Lour.）是一味临床常用于结直肠癌治疗的清热解毒类中药，但其活性成分山梗菜碱（Lobeline，洛贝林）详细的抗癌机制仍不完全清楚。 研究团队将 …

Lobeline, an alkaloid of Lobelia inflata (Indian Tobacco), is a nicotinic receptor antagonist, inhibitor of VMAT-2 function and has low affinity for the dopamine and serotonin transporters. MA …

Lobeline inhibits nicotine -evoked dopamine release and [3H]nicotine binding, thus acting as a potent antagonist at both alpha3beta2 (*) and alpha4beta2 (*) neuronal nicotinic receptor …

洛貝林(Lobeline),別名山梗菜鹼、祛痰菜鹼,。 興奮 頸動脈體 化學感受器 而反射性興奮 呼吸中樞 。 用於 新生兒窒息 、 一氧化碳 引起的 窒息 、 吸入麻醉 劑及其它中樞抑製藥（如 阿片 、 …

2025年2月19日 · Lobeline has CNS and peripheral effects similar to nicotine; however, it is not as potent. It initially causes CNS stimulation followed by respiratory depression. Lobeline has a …