2022年4月15日 · Herein, a nanocomposite probe was constructed by adsorbing functionalized DNA onto the surface of ZIF-8 pre-embedded with DNA polymerases and nicking endonuclease for live cells imaging and sensitive detection of ATP.

2017年4月7日 · We report herein the first example of using nanoscale ZIFs (i.e., ZIF-90), self-assembled from Zn 2+ and imidazole-2-carboxyaldehyde, to target subcellular mitochondria and image dynamics of mitochondrial ATP in live cells. Encapsulation of fluorescent Rhodamine B (RhB) into ZIF-90 suppresses the emission of RhB, while the competitive ...

2023年7月15日 · Design and working principle of ZIF-8 for enhancing the live-cell microRNAs imaging of DNAzyme-based DNA walkers. First, ZIF-8 is cracked and released Zn 2+ and DNAzyme-based DNA walker in acidic environment of cancer cells; Second, the target replaces locking probe, and DNAzyme activity is activated.

2017年4月14日 · With this method, we are able to image mitochondrial ATP in live cells and study the ATP level fluctuation in cellular glycolysis and apoptosis processes. The strategy reported here could be further extended to tune nanoscale ZIFs inside live cells for targeted delivery of therapeutics to subcellular organelles for advanced biomedical applications.

沸石咪唑酯骨架材料zif-8是一种孔径可调、孔隙率高、生物相容性好、稳定性高的新型金属有机框架材料（mofs），可广泛应用于吸附、储气、催化等领域。

2022年10月26日 · Herein, we prepared a series of single-crystalline ordered macro–microporous zeolitic imidazolate framework-8 (SOM-ZIF-8) with different macropore sizes of 180, 270, and 360 nm for lipase immobilization and investigated their performance in a …

2024年10月1日 · To further explore the antibacterial mechanism of ZIF-8@Au@Pt NPs, the antibacterial activities were investigated by a live/dead dual-color fluorescent stain kit, in which SYTO9 can stain all cells and displays green fluorescence, while propidium iodide (PI) can penetrate dead cells and exhibits red fluorescence [45].

ZIF, the Zoomable Image File format, alternatively also known as the Zoomify Image File format, is an open-source, web-friendly, multi-resolution, pyramidal tiled file format, based on TIFF, designed to enable interactive panning and zooming of extremely large images, especially over the World Wide Web and other Internet services.

zif，即类沸石咪唑酯骨架材料，是利用zn(i)或co(ii)与咪唑配体反应，合成出的类沸石结构的mof材料。与沸石分子筛相比，zifs材料拥有更丰富的孔笼孔道结构，其中有的拓扑结构是沸石分子筛中未出现的。

We report herein the first example of using nanoscale ZIFs (i.e., ZIF-90), self-assembled from Zn2+ and imidazole-2-carboxyaldehyde, to target subcellular mitochondria and image dynamics of mitochondrial ATP in live cells. Encapsulation of fluorescent Rhodamine B (RhB) into ZIF-90 suppresses the emission of RhB